Dec. 21, 2022
Advice for founders on how to sell into healthcare: Amit Mehta - BuildersVC

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Amit Mehta is a General Partner at BuildersVC and an interventional radiologist. BuilderVC is a $450 million venture capital firm which invests in seed to series B across multiple industries.
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Hi everyone, thanks so much for joining me today.
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Today I'm talking to Amit Mehta.
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He's an interventional radiologist and a general partner at Builders VC.
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Builders VC is a $450 million venture capital firm.
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They invest across all verticals, including healthcare.
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I hope you guys enjoyed the conversation with Amit as much as I did.
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Amit, thanks so much for coming on the podcast.
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Really looking forward to this call.
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To start, if you want to give us a brief introduction and then we'll get right into it.
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Sure.
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So, I grew up in Canada.
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I spent my childhood in Toronto, went to school in Canada and then saw some need for some
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technology as I was moving through medical school and figured that I couldn't do it there
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in Canada.
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So, for residency, decided to come to the US and work specifically on some specific
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problems.
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So, I trained through the Harvard system at Mass General, did essentially all my training
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there, fellowship and then ran a lab, research lab there for a few years while I was doing
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residency and did a few other things that were of interest.
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But during that time, got interested in investing and startup and got involved in that whole
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ecosystem there.
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Once I finished training, I had a thesis to run that lab there but then decided, had spent
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an infinitesimally small amount of money on my medical school education compared to my
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cohorts in the US and felt bad.
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So, I said, I'm going to come back to Canada and not contribute to the brain drain.
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So, moved back to Canada and worked in Canada for a couple of years, again, trying to move
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forward some of these ideas that I was working on in telemedicine and teleradiology and all
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of this kind of stuff.
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In that process, my wife who was from LA hated the cold and said, we got to move somewhere
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warm.
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And so, in that journey, moved back to the US and kept going on all the things that I
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was doing.
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Tell me a bit more about what tech did you foresee that was not feasible in Canada and
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you hinted towards teleradiology and telemedicine.
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And was it not feasible because of reimbursement issues, regulatory issues or something else?
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Yes.
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Basically, all of the above.
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So conceptually, what I was working on when I was doing residency and fellowship was a
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combination of telemedicine but also applying telemedicine and teleradiology into the clinical
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trial sphere.
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And that didn't work in Canada for a couple of reasons.
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One, I mean, there was no concept of telemedicine from both a technologic infrastructure standpoint
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nor from a reimbursement standpoint.
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There was no drive to even innovate in that space, venture and startup and all of which
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now is very robust in Canada through Mars and through BDC and a lot of the entities
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that as a VC now, those entities are actually limited partners in our funds.
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There was none of that.
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This was 15 years ago.
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And so I tried to push this agenda of what at the time I thought was sort of revolutionary
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in terms of bringing care to underserviced areas, which was a big problem in Canada,
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right?
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Northern Ontario and lots of other places.
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There was just no appetite for it.
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And the extension of that was what I initially had dreamt of was working on a clinical trial
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company where we had some technology and some ideas around making clinical trials more efficient
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and subsequently, several years later, did start that company, ran that and then we sold
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that company last year to a public.
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So in the end, it turned out and there was fruition to all the goals, but in Canada,
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I just didn't feel like I could get it done.
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Have you seen, and I've had similar experiences with my startup in Canada and talking to the
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Ministry of Health here as their primary goal is being reelected and nothing else.
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Have you seen any changes now and if you were a resident or in med school now, would you
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have stayed in Canada or do you think things are more or less the same still?
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No, I think it's done a complete 180 and it's completely changed.
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I mean, we're sourcing a lot of our deals on the venture side from Canada.
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We have a mandate because these Canadian entities, Alberta Enterprise and a few others are LPs
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in our fund.
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We have a Canadian mandate that we need to spend a certain amount of money in Canada
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and we don't have trouble finding deals.
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So I think that entire innovation ecosystem has completely blossomed from the time that
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I was there and the difficulty what I had in terms of just the whole life cycle of a
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startup from fundraising to infrastructure to human capital.
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I just don't see that happening now.
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I mean, it's not, I don't think it's Silicon Valley, but it's also not as difficult it
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was when it was when I was doing it.
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Okay, yeah, that's good to hear.
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Let's go back to your childhood, Ahmed.
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Let's go back to when you were about 10, 15, maybe in high school.
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What did you want to be then?
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And once you were in med school, did you, most people in med school think they're going
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to be a doctor forever, as did I.
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When did that change for you?
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And did you say, okay, this isn't enough for me and I want to do something else or something
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more?
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I always wanted to be a doctor.
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I think I grew up in a family with physicians and all of the rest of, you know, typical
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sort of immigrant story, but I had a very, I think an interest in technology and a technological
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bent in terms of tinkering and, you know, ran illegal bulletin boards out of my attic
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and got in trouble with my parents and all of that kind of stuff when I was a kid.
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And so I was at an interest in technology.
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And so I was driven towards a technologic field and it was more finding the right time
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to start working on those ideas as opposed to trying to generate the idea or is it something
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I want to work on?
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I had determined I wanted to work on it very early.
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It was just, you know, back then it wasn't cool to be 17 and start a company as it is
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now, if you're 30, it's not cool.
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You need to be 15 to start a company.
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So that dynamic was very different.
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It was hard to get taken seriously as a 17, 18 year old, you know, and I mean, you guys
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are in Canada, you're in Canada, the back of the, I mean, I did the two year university
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four year med school thing.
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And so on top of that, I was going into being, you know, medical school really young, like
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16, 17.
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So it was hard to get, it was hard to be taken seriously.
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But I had those ideas and I was always working on those ideas as I kind of progressed through
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the system.
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So medicine was sort of, it was the day job and work on going through medical school and
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the academic component of it, but was working on those things at my own time.
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Okay, perfect.
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And why did you decide to pick intervention radiology?
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Primarily, again, like I'm at a very tech bent.
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It was very, I think it was a combination of a couple of things.
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One is, you know, you say, there's so many experiences shape who you are.
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So like I was telling you, like I went to medical school very early.
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Like I remember taking a primary care rotation and just patients just were like, you're too
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young to be my doc.
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Like I just was young and so people didn't take me seriously.
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So that was sort of steered me away from patient facing things almost off the bat because of
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this sort of this discrimination on age to a certain extent.
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But I did have a very tech bent.
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And so I was looking for things that were very heavy in that.
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So it almost fed me towards surgical specialties off the bat.
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And as I got further, I realized that maybe I'm a little bit ADHD and that, you know,
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I like to move very quickly and efficiently.
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And so radiology was something that was like that one.
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It wasn't as patient facing as I didn't want completely not patient facing, which, you
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know, interventional reality still is patient interaction.
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It's not all interpretation, but it was less patient facing.
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It was tech oriented.
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I could innovate in that space and it was still it was a high volume of cases moving
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very quickly, which was very attuned to my personality.
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So I think I was kind of lucky to find that early on that I found something that fits
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my personality.
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I never went through that concentration of is this the right thing for me or is this
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the right specialty?
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Like I loved it from the beginning and I've always loved I mean, to this day, I still
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enjoy it.
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Okay, perfect.
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You've had a lot of different experiences in the past 10 years.
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I'm and you know, someone would look at the resume and say, I'm a doesn't stick with things
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to an extent is tell me a bit more about joining your most favorite experience and then your
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least favorite if you'd like to.
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And what made the decision to were you like, I'm here for this job.
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I'm going to take this company from point A to point B when it's a point B, I'm going
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to leave or what was the thought process behind that?
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Yeah, it's funny.
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I think my detractors would say the opposite, I stick with things too long.
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So a lot of these Yeah, interestingly, I probably doing too many things and doing all of them
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at the same time as opposed to doing one and letting it go.
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But you know, the most interesting thing I think is definitely all for me as always been
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is been venture and being a GP and a fund and investing and all of the cool ideas and
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things you think about and figuring out a process of how to be a good investor and how
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to work on that.
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I mean, absolutely, that's been it's been fun.
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And it's been the exposure is incredible.
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You get to see things and touch things and do things that just you don't get any other
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way.
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Interesting way I would tell you that the flip side of that probably and I wouldn't
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say this is the worst experience, but the most difficult has been starting and selling
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this company like it was eight years of, you know, it was 100 hour weeks just working,
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it was stressful.
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And you know, it was enjoyable to a certain extent for certain things.
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But at the same time, it was very stressful to running a company running a you know, being
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a physician doing venture like it was just probably a lot of things at the same time.
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But at the same rate, it was instrumental, I think, in in forming a foundation for me
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to be a better investor, you know, coming from an operator perspective, to becoming
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an investor is a very different mode than just trying to be a primary investor.
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You know, I mean, this morning, I spent, you know, three hours on calls going through with
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entrepreneurs looking at 2023 budgets and pro forma is an understanding how to work
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out, you know, how to run a pro forma to make sure that your cause doesn't exceed your revenue
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and that your human capital is being, you know, all of that only comes from operational
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experience.
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It's hard to get that unless you've seen hundreds and hundreds of things or you've spent time
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very focused and understanding that specific problem.
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And so it was an education by fire to a certain extent that I think has helped me as an investor
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Okay, perfect.
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A lot of people are looking at the rising interest rates, recession and kind of buckling
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down, keeping more money in cash, not deploying as much capital.
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You know, I look at public and private markets as two different entities.
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I don't even try and compare the two.
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What is your strategy moving over the next six or 12 months?
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Are you changing the way you look at startups?
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Are you looking for startups that are almost maybe revenue neutral and whereas before you
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would be have more laxity there?
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Is your investment thesis changing at all and are you deploying less or more capital
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over the next six or 12 months?
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So I mean, there's a personal component and then there's an institutional component, right?
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And I would say on the institutional side, we are a series A fund and a seed fund.
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And so what's just evolved in the venture landscape is sort of valuations more than anything else.
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I mean, we're still with the companies we were investing in already were in a situation
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where they were often were not that revenue positive.
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They were beyond proof of concept, beyond seed stage companies, but they had not hit
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that hockey stick of growth yet.
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So that hasn't changed.
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I mean, we're still investing at the same level and series.
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It's just some of the deal metrics have changed in terms of valuations, in terms of ownership
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or what we're doing for that company.
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Our stage size of check and involvement in the company has stayed the same as it was
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a year or two or five ago.
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So we're not, you know, there's just these, I think, you know, part of the benefit of
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now being older is that this is cyclical, right?
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And I've been through a couple of cycles of this now and understand that all we did really
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honestly be truthful with you is we told our companies that, you know, you should stockpile
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30 months, you know, going out into the fundraising environment in the next 12 to 18 months is
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going to be really difficult unless you are one of the winning companies.
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I mean, if you're a winning company, there is money in the system, venture, whatever
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you want to say that has to be deployed, right?
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By definition, funds work by deploying capital.
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So that capital is going to be deployed to the winners.
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And so if you're a winner, it should be okay, but if you're on the precipice of being a
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winner or you're not a winner, then you need to hoard cash now.
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It's not that we think you're a bad company.
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It's just your life cycle over the next 18 months is going to be very different than
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a year ago when everyone was falling all over themselves.
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We had deals that were valued at 100 X ARR.
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I mean, I haven't seen a deal like that in nine months.
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Like, I mean, if you try to sell a deal now at 100 X ARR, people will just laugh at you
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and be like, you know, good luck.
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So I think that's the biggest shift is be conservative and, you know, we all hope our
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companies are winners.
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So if they're a winner, it's great.
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We can help them raise money.
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But if they're not or their inflection point is going to be a little more difficult.
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Okay, perfect.
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Talk to me about your first LP.
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How long did it take to get that investment?
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And does it get much easier after the first LP?
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There's a few GPs with smaller funds who listen to this, and I think they'd be very interested
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in the answer.
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Contrary to what everyone else says, I find fundraising the most difficult thing in the
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world.
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I mean, every single meeting is a different minefield.
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So in essence, right, in venture, I mean, as well as personal probably trackers, if
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you've had a track record of great investments, it speaks for itself.
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And this is like when you run a company.
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You know, when there's sales, everyone's happy.
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When there's no sales, then all of the problems start to come up.
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And, you know, this person is not doing this and that person is not doing this or this
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infrastructure is broken.
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So in venture, if your funds are doing well and you have returned that follow up meeting
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with an LP to ask for a check for the next fund is very straightforward because so look,
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we returned you 5x on our last fund.
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It's almost a fait accompli.
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Like, why wouldn't you put money into this next fund?
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The trouble is when your funds are not doing well, and you're asking for re-ups on checks.
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That's when it's difficult.
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But my philosophy has always been, you know, and this is somewhat medical, you know, driven
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in medicine into that if you're not doing something well, then maybe you need to look
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at some other, you know, don't kill people, like maybe pick another surgical specialist
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or something like you need to you need to pivot.
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And so luckily, our funds have done very well from the inception.
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And so we, you know, going into these LPs is more of a relationship driven fundraise
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rather than trying to prove our economics, our DPI and our, you know, everything has
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been good.
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So we haven't had that issue.
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Okay, perfect.
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When I think about my past investments, when I look at companies, I'm looking to invest
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right now, I usually look at the level of conviction I have and the potential reward.
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And usually sometimes I may have a lower level of conviction, but I'm getting in at a cheap
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valuation and there's a high level of reward.
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Talk to me about, I'll ask you about your best or your favorite investment first and
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we'll talk about your least favorite next.
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What was your level of conviction?
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What was the balance between your level of conviction and a potential reward in your
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favorite investment and then your least favorite?
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Yeah, I mean, I think that's a pretty difficult question to answer from a VC perspective.
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The decision is multifactorial, right?
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There's a myriad of things that go into deciding whether you make an investment, whether it's,
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you know, of which the entrepreneur is very important, the total market is important,
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the product is important, fit, all of those things go into that decision.
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I would say I've never made an investment that I didn't have a hundred percent full
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conviction on.
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Whatever got me to that level of conviction was different probably every time.
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And there's ebbs and flows.
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And like I think, again, like I said, as you understand, there's cycles in this stuff,
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there's different things at different times that are applicable, especially in healthcare,
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right?
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Healthcare investing is probably to me is more difficult than some of the other disciplines
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just because it's so heterogeneous.
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There's multiple verticals, there's payers, there's providers, there's patients, there's
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a FinTech component, there's a tech component, there's, you know, applicability in the market,
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there's hospitals, ACOs, clinics, I mean, it goes on and on and on, right?
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And so it's always at the end of the day, it's always been a hundred percent conviction,
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but the conviction has been around different things.
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And that's dependent on the cycle we're in, you know, decreasing reimbursement rates,
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is there opportunity of FinTech opportunities in healthcare right now, as opposed to, I
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think, during COVID and the pandemic, there was a lot of opportunity for remote care and
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moving tertiary care outside of the hospital to the home, remote monitoring, IOT.
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So there's a different, the conviction comes around different elements of the opportunity
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at the time in the cycle we're at.
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Okay, perfect.
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Amit, would you rather have a life of many successes, but no major success?
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Or would you rather have a life similar to Vincent van Gogh's?
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He had massive, what we would call failures, was not recognized in his own life, you know,
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infamously famous now.
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Would you rather have Vincent van Gogh's life, a hard life, lots of failures, no success
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while you were living, or a life of many successes, but you're not known, and you don't change
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the world in any substantial capacity?
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Yeah, I mean, I don't think the human brain is probably not wired to enjoy failure.
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So I don't, you know, I think it'd probably be the former.
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Yes, obviously, success feels good.
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But success and failure, I think, again, are also probably very, it's a very individual
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term.
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And what one may, you know, if you have an exit out of your company for $50,000, is that
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successful versus someone who has a $50 million or a $500 million exit?
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Once you've had a $500 million exit, then your next exit needs to be $5 billion, or
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you weren't successful.
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You know, your next exit at $500K is not successful, right?
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So I think some of that is just shaped on your experience.
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And what I've done, you know, I've tried to build a career around three facets, right?
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So there's a medical career, an actual physical operating career, the investment career, and
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then the innovative or the operator career of starting a company, running a company,
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and tried to bring all three of those things together to optimize what I can do as an investor,
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as a physician, and as an operator for each of those.
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So I think, I feel like success has been different in each of those things, and failure has been
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in each of those things.
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Like, you know, our failure on the operating side is very different than failure on the
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investing side, which means we lost $15 million in investment.
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Failure on the operating side is that we couldn't motivate our salespeople to make enough sales.
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You know, the magnitude of importance of those things are very different as for me as an
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individual, but as in my responsibility in each of those entities, is probably of equal
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importance.
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So it's just very dependent on what lens you're looking at it from, but I would say I don't
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like, I mean, I don't like failure.
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So I'm going to go with success more than failure.
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Okay, perfect.
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What advice do you have for founders trying to sell to health systems right now?
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How much should they, a lot of founders that come to me, they focus too much on clinical
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ROI and not enough on immediate financial ROI, which I feel a lot of health systems,
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ACOs, family health teams are more focused on and decisions are made more on financial
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ROI.
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You have a lot more experience than I do.
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It's more of a selfish question for me and what advice I should give to my founders right
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now.
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What advice would you give to founders trying to sell into health systems right now?
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You know, I said the thing that I think is the hardest thing to do in the world is to
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raise money from LPs.
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Let me give you a very, very close second is to sell into a hospital system.
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So, you know, selling to a hospital system, the problem is the incentives are probably
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perverse and it's very difficult to understand what those are in that the driver for a hospital
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system may not be what you...
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If you are not a provider or been on the medical staff or a CMO or a CMIO, whatever it may
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be, you may not understand what the driver is for that hospital system, hospital administrator
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who, you know, not a popular thing to say, but as we all know, they seem to rotate every
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two months.
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There's a new hospital administrator, right?
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The velocity of change in the hospital administrator is incredible.
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So I would say try to focus on products that probably don't sell to the hospital first,
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but saw more of a large clinical need where the hospital is where you end up as your larger
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clients once you've established a base with whatever else it may be.
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So telemedicine is a good example.
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Telemedicine is very applicable to hospital interactions, but maybe start in another setting,
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both prove out your infrastructure, prove out your business model, prove out your finances,
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and then that's the bigger fish to go after.
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Okay, perfect.
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Yeah, I mean, A16Z recently released their report about the pay-vider model and their
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banking on BTC consumer health.
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Let's talk a bit about the reimbursement structures in healthcare.
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And then particularly, do you think healthcare should be profitable?
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If so, what parts of healthcare should be profitable?
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Should it be primary care?
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Should it be more acute care, hospital care?
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As it stands now, the most profitable parts of healthcare are cancer therapy, surgeries,
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which I think should be perhaps at least profitable.
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And I also think innovation in healthcare should be decoupled from delivery of healthcare.
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So I'd like to get your thoughts on innovation and delivery in healthcare.
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Should they be different financial systems and incentives for both and profitability
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in healthcare?
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Yeah, that's a very interesting question.
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So I've worked in the US system and the Canadian system, and we've done a lot of work in the
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UK system.
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So I've seen three very different models of healthcare, worked in two of them and worked
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very closely in the third.
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And so I will tell you, I think my personal opinion is there's probably no optimal system.
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But the answer to your first question is I do think healthcare should be profitable.
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I think there's a governor on how profitable and some of that is ensuring that it needs
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... I think part of the problem right now is, and CMS and some of the other systems
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have made an effort towards this, but there is an essential decoupling of quality versus
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reimbursement.
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And we're moving towards trying to fix that, but in a lot of ways that's almost not fixable
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or has not been fixed.
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But I think that it is reasonable to make it a profitable system where you're based
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on quality and pay for quality.
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And the reason I say that is, I know you're saying a decouple innovation, but I think
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innovation is driven by that.
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People do go into medicine because financially it is satisfying.
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You do make good money as a doctor.
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It's not a secret.
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If you start eliminating the financial benefit, if you're building a system from de novo
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and that there's that opportunity, that's different.
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But in the current system, if you said, well, doctors are going to start making a 10th of
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what they make now, you're going to lose some of the best and brightest from going into
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medicine and then quality will drop and et cetera.
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There's a fallout from that.
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So I think in the confines of the current system, it does need to be profitable, but
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I do believe insurance companies have taken this to a different level and the system has
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been perverted in order to have oversized returns for United.
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If you look at just look at their filing, the amount of money insurance is making is
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out of proportion to what we see on the street and what happens in terms of patients being
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either not getting a pre-op or being steered towards certain providers or whatever is happening
401
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for the people in the trenches.
402
00:25:14,560 --> 00:25:16,320
Okay, perfect.
403
00:25:16,320 --> 00:25:18,800
Let's talk about tailwinds.
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One tailwind I'm banking on as a hybrid home care model for acute care.
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00:25:23,760 --> 00:25:25,440
Take me back 10 years.
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What are some tailwinds you were identifying then that you were right about and what are
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some you were wrong about?
408
00:25:33,360 --> 00:25:39,540
So I sort of built at Builders our healthcare thesis around sort of four pillars of which
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I think they've all sort of come true.
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So the first and the paramount was the concept of moving care from hospital, surgery center,
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tertiary care center to the home as much as possible, cheaper, faster, better, more convenient
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and using technology in order to do that.
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The first iteration or generation of that tech was sort of remote monitoring, IOT, host
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of techniques such as that companies like Lavongo and even Fitbits and that kind of
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thing have used.
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So a concept of moving, it's not necessary to treat a copper strep in a tertiary care
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hospital at three grand a visit.
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You can do that at home, telemedicine for 15 bucks.
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So that is a generic concept of moving care away from the sort of very expensive to cheaper
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care centers.
421
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That was a big thesis of which we made some investments around that happening into a company
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called Carbon Health and a couple of others.
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Second was a true understanding that I think the omics space is going to revolutionize
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a lot of what we do whether it's genomics, protanomics, metabolomics, radioma, all of
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these omic kind of things.
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Basically driven towards a better understanding of each individual rather than at a population
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level.
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And so I can tell you personally, we see this all the time, people that come into the emergency
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room, they have abdominal pain, trigger a CT, which is a thousand dollar test.
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They had some bad chicken and they go home because it's a normal CT.
431
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I think we had a test at home that we knew that you had a, you know, whatever it may
432
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be, a tryptophan allergy and you probably shouldn't drink this kind of red wine.
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And it's because you had that red wine with your chicken and that's why you have belly
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pain.
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00:27:26,560 --> 00:27:30,140
And we just saved the system a thousand dollars, an ER visit and a CT scan.
436
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So that personalized medicine component of it, I think is coming.
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And we're seeing that with companies like Everly Well and a lot of the home testing,
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you know, home testing has become much more robust and a lot of companies doing so just,
439
00:27:42,760 --> 00:27:45,280
you know, either whether it's blood, urine.
440
00:27:45,280 --> 00:27:51,520
I was on the board of a company that has a breast cancer detection algorithm out of tears.
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So lots of that kind of stuff, saliva, tears, sweat, blood, urine, stool, that having these
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tests that will give us a lot more information about an individual that can give us more
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preventative healthcare.
444
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Number three was some novel techniques around the finance of healthcare.
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So we were an early investor in Oscar.
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This is a healthcare insurance company in New York that took advantage of a lot of the
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Obamacare.
448
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They were doing some very interesting things with tech.
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You know, they were able to, for example, they were one of the first ones who would
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give you a fitness tracker.
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And if you were using the fitness tracker and walking a certain amount every day, you
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would get a reduction on your rates.
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They understood, you know, they would look at clusters of claims and they, you know,
454
00:28:35,840 --> 00:28:39,920
I remember a very good example where they had a cluster of asthmatic kids in one area
455
00:28:39,920 --> 00:28:44,280
in New York and they realized what was happening was that there was an infestation of bed bugs
456
00:28:44,280 --> 00:28:47,880
and these bed bugs were eliciting asthmatic reactions in these kids.
457
00:28:47,880 --> 00:28:52,520
So the insurance company paid for exterminators to go exterminate these bed bugs because the
458
00:28:52,520 --> 00:28:57,280
Senate exterminated it out for 59 bucks was cheaper than three hospital visits for the
459
00:28:57,280 --> 00:28:58,280
asthmatic kid.
460
00:28:58,280 --> 00:29:02,560
So, you know, all the understandings of sort of payment mechanisms, both whether it's a
461
00:29:02,560 --> 00:29:07,640
pay-by-their, but whether it's third-party administrators, whether it's ACOs or whatever
462
00:29:07,640 --> 00:29:12,280
it may be, the novel mechanisms of payment for healthcare that can make the system more
463
00:29:12,280 --> 00:29:18,440
efficient and not necessarily do sort of just the conventional insurance model.
464
00:29:18,440 --> 00:29:22,200
And then the last is just AI as a generic catch-all for sort of things.
465
00:29:22,200 --> 00:29:27,200
And, you know, generative AI and diagnostic AI, I hesitate to use that term because every
466
00:29:27,200 --> 00:29:32,320
company we look at now in 2022 has some AI component and it doesn't really mean anything.
467
00:29:32,320 --> 00:29:39,000
But I think there is a rule, especially as a radiologist, we see a ton of AI and my clinical
468
00:29:39,000 --> 00:29:43,200
trial company that we had worked with that did almost all the FDA approvals for all the
469
00:29:43,200 --> 00:29:45,200
AI algorithms and radiology.
470
00:29:45,200 --> 00:29:49,480
So we had a lot of exposure and a lot of work in that space.
471
00:29:49,480 --> 00:29:53,520
But I think that's something that is going to keep on growing.
472
00:29:53,520 --> 00:29:59,120
Okay, I think I have a trillion questions.
473
00:29:59,120 --> 00:30:05,840
The one thing I'll ask first, I ask you the next question, the fitness tracker for reduction
474
00:30:05,840 --> 00:30:07,920
on rates, did that work?
475
00:30:07,920 --> 00:30:08,920
No.
476
00:30:08,920 --> 00:30:11,040
So I think there was two problems.
477
00:30:11,040 --> 00:30:15,800
One is they were using Misfit, which was an old school tracker, which, you know, there's
478
00:30:15,800 --> 00:30:17,440
a limited amount of information.
479
00:30:17,440 --> 00:30:21,720
And we've now invested in a company that is actually the reiteration of Jawbone.
480
00:30:21,720 --> 00:30:25,360
I don't know if you remember that Jawbone had a headset and a boombox.
481
00:30:25,360 --> 00:30:29,160
Well, they've like come back and they actually have a fitness tracker that they went and
482
00:30:29,160 --> 00:30:33,420
bought a bunch of technology for a bunch of sensors, green light sensors from Phillips.
483
00:30:33,420 --> 00:30:38,680
But they're building an ecosystem around a full fitness tracker for humans.
484
00:30:38,680 --> 00:30:42,420
And so you think about it sort of like in your car where you get a red light for when
485
00:30:42,420 --> 00:30:44,160
something's going wrong with the engine.
486
00:30:44,160 --> 00:30:49,160
It's a tracker for it's tracking everything 24 seven in real time, but then informing
487
00:30:49,160 --> 00:30:50,580
you when there's when there's an issue.
488
00:30:50,580 --> 00:30:53,800
So I think tracker technology has progressed a significant amount.
489
00:30:53,800 --> 00:30:54,800
That was number one.
490
00:30:54,800 --> 00:30:57,680
And number two, just adoption by people.
491
00:30:57,680 --> 00:31:02,080
You know, at the end of the day, the problem with that technology was people weren't walking.
492
00:31:02,080 --> 00:31:06,480
Like it wasn't enough of an incentive for them to say, if I get three dollars off my
493
00:31:06,480 --> 00:31:10,160
insurance premium, but I have to walk seven miles a day, I'm not going to do it.
494
00:31:10,160 --> 00:31:11,700
We have more data now.
495
00:31:11,700 --> 00:31:16,960
What is beneficial both from a human hack perspective, from both a diet, from sleep,
496
00:31:16,960 --> 00:31:18,480
from all of these things.
497
00:31:18,480 --> 00:31:20,760
Again, we're talking about personalized medicine, right?
498
00:31:20,760 --> 00:31:23,920
Ketosis, prognomics, intermittent fasting, walking, all of these things.
499
00:31:23,920 --> 00:31:28,280
We just have a better understanding so we can be more meaningful now about what we're
500
00:31:28,280 --> 00:31:32,840
what an insurance company would recommend if you're trying to get a true reduction in
501
00:31:32,840 --> 00:31:33,840
rates.
502
00:31:33,840 --> 00:31:35,960
OK, perfect.
503
00:31:35,960 --> 00:31:39,200
Let's talk about how we make decisions.
504
00:31:39,200 --> 00:31:42,640
And the basis of this is health care is a need.
505
00:31:42,640 --> 00:31:43,980
It's not a want.
506
00:31:43,980 --> 00:31:46,400
We pay more for wants than our needs.
507
00:31:46,400 --> 00:31:51,680
If we look at Robert Cialdini's principles of marketing, and I'm a big fan of his reciprocity,
508
00:31:51,680 --> 00:31:57,680
commitment, consistency, social proof, liking and scarcity, needing something is not a principle.
509
00:31:57,680 --> 00:32:02,760
How do we gamify health care so prevention is a want, not a need?
510
00:32:02,760 --> 00:32:05,680
Yeah, I mean, it's interesting.
511
00:32:05,680 --> 00:32:11,920
I would say, if I put my investor hat on, I don't think I'm not prepared right now to
512
00:32:11,920 --> 00:32:16,720
make bets in gamifying health care just because human behavior, the way the system is set
513
00:32:16,720 --> 00:32:19,120
up probably doesn't lend itself to being successful.
514
00:32:19,120 --> 00:32:22,920
I think the things that we've the companies we've seen have tried to gamify things have
515
00:32:22,920 --> 00:32:25,760
not traditionally been overly successful.
516
00:32:25,760 --> 00:32:30,400
Not that it can't be done in specific things for children, for you know, it works.
517
00:32:30,400 --> 00:32:35,240
But I think as an overall health care system, I think that's difficult to do.
518
00:32:35,240 --> 00:32:41,480
So I think, you know, for me personally, some of that the motivation to do that again is
519
00:32:41,480 --> 00:32:44,840
I strongly believe, unfortunately, or fortunately, is driven by money.
520
00:32:44,840 --> 00:32:49,400
You know, if your insurance rates are lower, we've seen and shown that people are motivated
521
00:32:49,400 --> 00:32:50,480
to do things.
522
00:32:50,480 --> 00:32:53,920
And then there's an upper and a lower band of what is considered reasonable, right?
523
00:32:53,920 --> 00:32:58,600
Like, you know, if we said to you, we'll reduce your insurance by, like I said, $5, but you
524
00:32:58,600 --> 00:33:00,720
have to walk 10 miles a day, you're not going to do it.
525
00:33:00,720 --> 00:33:05,000
But if we reduce your insurance by $50, and you have to walk three miles, maybe you'll
526
00:33:05,000 --> 00:33:06,000
do it.
527
00:33:06,000 --> 00:33:10,120
So there's some upper and lower band of human dynamics that you just need to understand.
528
00:33:10,120 --> 00:33:14,120
And we're looking and working with insurance providers who are trying to figure that out.
529
00:33:14,120 --> 00:33:18,000
You know, in a they're trying to figure out in a smaller cohort, we're working with a
530
00:33:18,000 --> 00:33:21,160
company that works only with small businesses, and they have a lot of healthy population.
531
00:33:21,160 --> 00:33:24,280
And so they're able to do that because they are there.
532
00:33:24,280 --> 00:33:27,280
There's not a lot of variation between their sickest and their healthiest person.
533
00:33:27,280 --> 00:33:29,920
So they have an internal control that they can look at.
534
00:33:29,920 --> 00:33:36,680
So I think it's it's understanding human behavior and human dynamic, and then trying to layer
535
00:33:36,680 --> 00:33:44,160
on realistic things that will allow those things to be to be valuable.
536
00:33:44,160 --> 00:33:47,160
And I remember, you know, there was a time when I was looking at, you know, trying to
537
00:33:47,160 --> 00:33:48,160
health hack myself.
538
00:33:48,160 --> 00:33:51,600
And I was watching these movies, Game Changers and Fat, Sick and Nearly Dead.
539
00:33:51,600 --> 00:33:54,520
And this guy was like juicing himself across the country.
540
00:33:54,520 --> 00:33:58,520
And I remember I live in Texas, but I remember this very vividly sat down with these these
541
00:33:58,520 --> 00:34:01,080
people in a in some barbecue place in Texas.
542
00:34:01,080 --> 00:34:03,760
And I said, you know, I'm juicing my way across the country.
543
00:34:03,760 --> 00:34:07,000
And the guy said, I'd rather die than not eat barbecue.
544
00:34:07,000 --> 00:34:10,240
And I think that that sentiment is probably there are people who are like, it doesn't
545
00:34:10,240 --> 00:34:11,240
matter.
546
00:34:11,240 --> 00:34:16,760
I'd rather smoke, drink, eat this, that, whatever, and just die happy than, you know, eat lettuce
547
00:34:16,760 --> 00:34:19,280
every day for 30 years and live an extra 20.
548
00:34:19,280 --> 00:34:22,600
I mean, there's just there's a human dynamic component that you have to understand.
549
00:34:22,600 --> 00:34:25,760
And it's very population driven in the population you're serving.
550
00:34:25,760 --> 00:34:29,920
And so it's a local and regional thing that you have to look at.
551
00:34:29,920 --> 00:34:33,720
And I think the companies that we're looking at are successful, have different models for
552
00:34:33,720 --> 00:34:34,720
different regions.
553
00:34:34,720 --> 00:34:35,720
Perfect.
554
00:34:35,720 --> 00:34:36,720
I'll say something a little bit inappropriate.
555
00:34:36,720 --> 00:34:37,720
I don't know if I should.
556
00:34:37,720 --> 00:34:38,720
I looked into juicing.
557
00:34:38,720 --> 00:34:45,720
And the reason I didn't do it is because there was a lot of mention of enemas.
558
00:34:45,720 --> 00:34:46,720
Yeah.
559
00:34:46,720 --> 00:34:49,720
Let's talk about each other.
560
00:34:49,720 --> 00:34:50,720
Yeah, exactly.
561
00:34:50,720 --> 00:34:54,960
But not for me, just to clarify.
562
00:34:54,960 --> 00:35:00,420
Let's talk about how to best incentivize people for healthy behavior.
563
00:35:00,420 --> 00:35:03,680
And I'll just give you two options to make it simple.
564
00:35:03,680 --> 00:35:08,360
Is it better to tug at loss prevention, which is essentially reducing rates or asking people
565
00:35:08,360 --> 00:35:13,320
for money and giving them back some if they meet the targets?
566
00:35:13,320 --> 00:35:19,960
Or is it better to tug at positive reinforcement or give them money on top of whatever the
567
00:35:19,960 --> 00:35:20,960
rates are?
568
00:35:20,960 --> 00:35:27,960
And it's more of a way of how you phrase or deliver this reward that is essentially the
569
00:35:27,960 --> 00:35:29,000
game here.
570
00:35:29,000 --> 00:35:31,480
Which one do you think is better?
571
00:35:31,480 --> 00:35:37,280
I would say all of the education and reading that I've done would illustrate that positive
572
00:35:37,280 --> 00:35:38,880
reinforcement is better than negative.
573
00:35:38,880 --> 00:35:42,000
Carrots are better than sticks.
574
00:35:42,000 --> 00:35:46,140
I would say that my real world experience of the same thing and me personally has been
575
00:35:46,140 --> 00:35:51,600
a reduction in rate or whatever is more motivating than the other side.
576
00:35:51,600 --> 00:35:54,120
So I don't know the answer to that question.
577
00:35:54,120 --> 00:35:56,720
We've looked at companies that have done both.
578
00:35:56,720 --> 00:36:02,240
So we've made investments in the secondary healthcare companies that run incentive programs.
579
00:36:02,240 --> 00:36:04,600
If you join the gym, you get a discount.
580
00:36:04,600 --> 00:36:07,760
If you do something else, you get a free Apple Watch.
581
00:36:07,760 --> 00:36:10,820
So that's the two things you're talking about.
582
00:36:10,820 --> 00:36:13,560
One is a reduction because you do some of the other is you get a free Apple Watch if
583
00:36:13,560 --> 00:36:15,560
you do this.
584
00:36:15,560 --> 00:36:20,060
And I think when they've studied that, it's been very, again, very heterogeneous depending
585
00:36:20,060 --> 00:36:22,560
on the population they're serving.
586
00:36:22,560 --> 00:36:24,880
And it's not one size fits all.
587
00:36:24,880 --> 00:36:28,960
A 75-year-old probably doesn't care about getting an Apple Watch.
588
00:36:28,960 --> 00:36:31,560
A 21-year-old wants an Apple Watch.
589
00:36:31,560 --> 00:36:36,320
The 21-year-old doesn't understand a reduction in rate will give you money that you can compound
590
00:36:36,320 --> 00:36:39,560
interest for the rest of your life and become a millionaire because you are healthy.
591
00:36:39,560 --> 00:36:44,880
The 75-year-old, so it's very different and you have to, it has to be applicable to the
592
00:36:44,880 --> 00:36:47,000
population that you're trying to serve.
593
00:36:47,000 --> 00:36:48,680
And that I think has been part of the problem.
594
00:36:48,680 --> 00:36:52,080
It's a one size fits all and it doesn't fit all.
595
00:36:52,080 --> 00:36:56,520
And so some of these innovative payments, like we have a family of four, we're fairly
596
00:36:56,520 --> 00:36:57,520
healthy.
597
00:36:57,520 --> 00:36:59,080
We use almost no healthcare.
598
00:36:59,080 --> 00:37:04,360
I pay a huge deductible, a huge premium every month, but we don't use healthcare because
599
00:37:04,360 --> 00:37:06,640
we're at a phase in our life where we're healthy.
600
00:37:06,640 --> 00:37:07,640
We'll need that later.
601
00:37:07,640 --> 00:37:11,680
Well, if you gave me an incentive to save some money and do things that would set up
602
00:37:11,680 --> 00:37:14,960
the insurance company and you could amortize that over some period of years, that would
603
00:37:14,960 --> 00:37:16,120
be a novel way of doing it.
604
00:37:16,120 --> 00:37:19,560
So we're looking at sort of those kinds of models where insurance companies are saying,
605
00:37:19,560 --> 00:37:21,200
let's take a small cohort.
606
00:37:21,200 --> 00:37:25,080
We have to analyze you as a cohort and see whether this fits for you.
607
00:37:25,080 --> 00:37:28,280
Traditionally, that's been too much manpower to do that.
608
00:37:28,280 --> 00:37:33,900
But now with algorithms, AI, whatever it may be, you can get that information on a much
609
00:37:33,900 --> 00:37:36,920
more efficient basis and make those decisions.
610
00:37:36,920 --> 00:37:41,860
So I mean, we looked at a company that on your phone, it can read all your vitals.
611
00:37:41,860 --> 00:37:47,040
So just by looking at the screen, it projects a red light, projects it off your skin, gets
612
00:37:47,040 --> 00:37:51,640
heart rate, temperature, O2 saturation, blood pressure, all from that.
613
00:37:51,640 --> 00:37:54,360
They're starting a pilot with an insurance company in Europe.
614
00:37:54,360 --> 00:37:56,520
So if you not even, you don't even have to check in.
615
00:37:56,520 --> 00:38:01,200
If you put the app on your phone, when you do FaceTime or whatever, or unlock your phone,
616
00:38:01,200 --> 00:38:03,200
it records that data and sends it to the insurance company.
617
00:38:03,200 --> 00:38:07,600
So now insurance company has a longitudinal view of your blood pressure, your heart rate,
618
00:38:07,600 --> 00:38:11,040
and now they can do your premiums without you having to do anything.
619
00:38:11,040 --> 00:38:16,280
That kind of novel stuff is I think where the future of this is where you can now, like
620
00:38:16,280 --> 00:38:21,480
you said, cancer and surgery, you can still pay for quality up there.
621
00:38:21,480 --> 00:38:25,400
Because the number of people using that is less out of the general population, but it's
622
00:38:25,400 --> 00:38:28,520
not the general population subsidizing that anymore.
623
00:38:28,520 --> 00:38:33,200
You can actually divert dollars where they need to go and save money where it doesn't
624
00:38:33,200 --> 00:38:37,940
need to go and have a very novel sort of payment and an insurance mechanism as opposed to this
625
00:38:37,940 --> 00:38:39,240
one size fits all.
626
00:38:39,240 --> 00:38:41,560
Yeah, I think that makes sense.
627
00:38:41,560 --> 00:38:48,960
Risk pooling is needed, but distribution of that risk can be triaged and personalized.
628
00:38:48,960 --> 00:38:51,200
What's the end game for you, Amit?
629
00:38:51,200 --> 00:38:57,640
If we define retirement by when you reach a point where every day is complete in itself,
630
00:38:57,640 --> 00:39:02,960
you're looking forward to things, but you're perfectly happy with the day as it was.
631
00:39:02,960 --> 00:39:05,420
Would you consider self-retire right now?
632
00:39:05,420 --> 00:39:10,900
And then the second part of this question is, I'll take you 50 years down the line.
633
00:39:10,900 --> 00:39:17,000
What do the last five years of your life look like in an ideal world?
634
00:39:17,000 --> 00:39:21,400
I think my wife probably has a very different answer to this question than I do.
635
00:39:21,400 --> 00:39:24,000
So for me, I don't think there is retirement.
636
00:39:24,000 --> 00:39:28,620
Part of what I like about investing and what I like is I pick a topic every year and go
637
00:39:28,620 --> 00:39:34,200
deep and try to understand, read, experience, whatever it may be around that topic.
638
00:39:34,200 --> 00:39:35,800
And there's no end of topics.
639
00:39:35,800 --> 00:39:37,920
And I enjoy doing that.
640
00:39:37,920 --> 00:39:39,840
So I'll continue to do that.
641
00:39:39,840 --> 00:39:44,480
And as long as I can be in it, obviously, there's a potential finite life as an investor.
642
00:39:44,480 --> 00:39:47,360
I mean, if your funds aren't returning, then there is no next fund.
643
00:39:47,360 --> 00:39:50,080
And it may be self-fulfilling that it's over for me.
644
00:39:50,080 --> 00:39:57,600
I'll continue to do the intellectual and experiential investigation that I do now on a yearly basis.
645
00:39:57,600 --> 00:40:02,920
But I think there's a physical component to when do you tire out?
646
00:40:02,920 --> 00:40:10,680
I stand in a lab 13 hours a day wearing lead, heavy lead for when I'm doing cases.
647
00:40:10,680 --> 00:40:14,880
At some point, physically, you wear out from being able to do that.
648
00:40:14,880 --> 00:40:15,880
But I'm not at that point.
649
00:40:15,880 --> 00:40:17,480
So I think I enjoy that.
650
00:40:17,480 --> 00:40:21,520
I'm now that I'll keep doing that until physically I'm not capable.
651
00:40:21,520 --> 00:40:24,280
But one thing that I've learned to do is multitask.
652
00:40:24,280 --> 00:40:28,880
And so while I can pursue these intellectual things at my level of my satisfaction, I'll
653
00:40:28,880 --> 00:40:30,980
just keep doing that till I can.
654
00:40:30,980 --> 00:40:35,360
So I don't know what the last five years, that last five is.
655
00:40:35,360 --> 00:40:40,240
I think there's a sentence that, tell me how I'm going to die so I can avoid it.
656
00:40:40,240 --> 00:40:47,600
So when that's coming, I hope I have some personalized medicine, genomic, proteomics
657
00:40:47,600 --> 00:40:53,240
markers that will tell me that you have 447 days left.
658
00:40:53,240 --> 00:40:54,520
Would you want to know?
659
00:40:54,520 --> 00:40:56,280
Yeah, I think I would.
660
00:40:56,280 --> 00:41:00,160
I mean, my personality is I'd rather know than not know.
661
00:41:00,160 --> 00:41:01,900
Both our kids, I'm a radiologist.
662
00:41:01,900 --> 00:41:04,640
We ultrasounded them in the first time.
663
00:41:04,640 --> 00:41:07,800
We knew what sex of kids we were going to have before we had them.
664
00:41:07,800 --> 00:41:08,800
There was no surprises.
665
00:41:08,800 --> 00:41:10,880
We're not doing, there was no gender reveal stuff.
666
00:41:10,880 --> 00:41:15,680
So yeah, I've always been a personality that I'd rather know and deal with what it is and
667
00:41:15,680 --> 00:41:17,880
have the knowledge rather than the surprise.
668
00:41:17,880 --> 00:41:19,760
The surprise doesn't engage me.
669
00:41:19,760 --> 00:41:20,760
Interesting.
670
00:41:20,760 --> 00:41:26,160
What's the perfect birthday for you?
671
00:41:26,160 --> 00:41:31,160
You know, I mean, I like to, you know, this sort of, I like to work.
672
00:41:31,160 --> 00:41:32,480
Like I like to do things.
673
00:41:32,480 --> 00:41:37,000
And so it doesn't necessarily have to be medicine or investing or these other things that I
674
00:41:37,000 --> 00:41:38,840
do, but active things.
675
00:41:38,840 --> 00:41:41,320
So obviously spend time.
676
00:41:41,320 --> 00:41:42,560
Family is obviously very important.
677
00:41:42,560 --> 00:41:49,160
You know, we have young kids, so probably that's the majority of it is that carve out
678
00:41:49,160 --> 00:41:55,040
time specifically to be with family during what is usually a very hectic week.
679
00:41:55,040 --> 00:42:01,720
Do you work on your birthday?
680
00:42:01,720 --> 00:42:04,200
I work if I have to.
681
00:42:04,200 --> 00:42:11,440
If I, if I can maneuver out of it, I would, but if I have to, I would.
682
00:42:11,440 --> 00:42:17,480
Would you classify yourself as an operator, someone excellent at execution or a visionary?
683
00:42:17,480 --> 00:42:23,840
And when you look at a founding team, do you look for both and which one is easier to replace
684
00:42:23,840 --> 00:42:27,600
or find source externally from your network?
685
00:42:27,600 --> 00:42:31,800
It's an interesting question.
686
00:42:31,800 --> 00:42:35,320
It's hard to say you're a vision, in my opinion, to say you're a visionary without being an
687
00:42:35,320 --> 00:42:36,760
egotistical visionary.
688
00:42:36,760 --> 00:42:39,640
So I'm going to, I'm going to dance away from that.
689
00:42:39,640 --> 00:42:45,240
But I think, yeah, my, I think my skillset has been more around strategy and vision than
690
00:42:45,240 --> 00:42:46,240
operation.
691
00:42:46,240 --> 00:42:51,120
You know, when we accepted this company, my company, I mean, I got on the ground and plugged
692
00:42:51,120 --> 00:42:57,560
in computers and wrote SOPs and did whatever it took as an operator, more as a skillset,
693
00:42:57,560 --> 00:43:02,480
learning how to do it so that, you know, when someone failed at it, I was the backup, I
694
00:43:02,480 --> 00:43:03,600
could do it.
695
00:43:03,600 --> 00:43:08,040
I wouldn't say I enjoyed the operational component as much as the strategy, vision, guidance
696
00:43:08,040 --> 00:43:09,040
part of it.
697
00:43:09,040 --> 00:43:12,240
And so I think also, you know, as you look at things that you do in your life and you
698
00:43:12,240 --> 00:43:16,080
converge into things that are more your personality, you know, as it takes time to figure that
699
00:43:16,080 --> 00:43:20,360
out, you know, that's why I prefer to be on the board of a company and help with direction
700
00:43:20,360 --> 00:43:26,200
and strategy using the experience from being an operator to help them rather than, than
701
00:43:26,200 --> 00:43:27,200
being the operator.
702
00:43:27,200 --> 00:43:29,720
Having said that, we've been toying with being an operator again.
703
00:43:29,720 --> 00:43:32,920
Your friend of mine has come to me and said, like, let's start another company.
704
00:43:32,920 --> 00:43:39,680
And so maybe that does come again, but it has to be the right idea and the right execution.
705
00:43:39,680 --> 00:43:45,400
But I prefer the, you know, he's an, he's an incredible operator and has operated at
706
00:43:45,400 --> 00:43:47,160
a very high level.
707
00:43:47,160 --> 00:43:50,440
So we compliment each other really well and that I'm more strategy vision.
708
00:43:50,440 --> 00:43:53,520
He's very operate, he's less strategy vision.
709
00:43:53,520 --> 00:43:56,280
And you know, so that compliment works well.
710
00:43:56,280 --> 00:44:01,240
And do you look for both in a founding team and which one is easier to source from your
711
00:44:01,240 --> 00:44:02,240
network?
712
00:44:02,240 --> 00:44:03,240
I mean, absolutely.
713
00:44:03,240 --> 00:44:06,200
I look for it in a founding team.
714
00:44:06,200 --> 00:44:08,640
I mean, it's always in the back of your mind.
715
00:44:08,640 --> 00:44:12,320
The issue is more at the stage of when you're making an investment.
716
00:44:12,320 --> 00:44:17,440
So if it's a series CD, whatever, I mean, they figured it out, right?
717
00:44:17,440 --> 00:44:20,040
I mean, you're not getting to a hundred million in revenue.
718
00:44:20,040 --> 00:44:26,360
If the CEO is a tech guy, was no tech person who has no operational experience and can't
719
00:44:26,360 --> 00:44:27,360
motivate people.
720
00:44:27,360 --> 00:44:28,800
Like it's just not going to happen.
721
00:44:28,800 --> 00:44:29,800
Right.
722
00:44:29,800 --> 00:44:35,080
Or it's very rare that that happens at the stage where we invest, which is seed and a,
723
00:44:35,080 --> 00:44:39,920
all of that is very important, but hasn't necessarily always manifested.
724
00:44:39,920 --> 00:44:44,640
So we see lots of companies where the CEO is great for the seed or for the early a,
725
00:44:44,640 --> 00:44:49,880
but once you get to a B or a C, they really need to step aside and bring in adult supervision,
726
00:44:49,880 --> 00:44:52,000
so to speak, because it's not there.
727
00:44:52,000 --> 00:44:56,320
They're a great founding CEO and they're the ones, you know, two guys in a garage, you
728
00:44:56,320 --> 00:45:01,280
know, all of that sort of stuff, but they're not the ones that sit with an investment bank
729
00:45:01,280 --> 00:45:03,760
to negotiate, you know, book running an IPO.
730
00:45:03,760 --> 00:45:05,600
I mean, that's not who they are, right?
731
00:45:05,600 --> 00:45:08,840
They don't, the attention to detail, the experience, whatever it may be.
732
00:45:08,840 --> 00:45:12,400
And so that, I think it's very much dependent on what stage you're investing at to figure
733
00:45:12,400 --> 00:45:14,560
out who the right founders are.
734
00:45:14,560 --> 00:45:15,560
Okay.
735
00:45:15,560 --> 00:45:22,440
You know, something I'm doing right now is looking at companies that have made it and
736
00:45:22,440 --> 00:45:25,240
going back to see if I would have invested in them.
737
00:45:25,240 --> 00:45:29,560
And oftentimes the answer I'm getting is no.
738
00:45:29,560 --> 00:45:33,880
The companies I'm talking about, I'll just say some names as Romans and Four Hymns, you
739
00:45:33,880 --> 00:45:39,640
know, they've done really well and they're pivoting to more being almost at home hybrid
740
00:45:39,640 --> 00:45:43,760
health system, which is great, but that's not what they were when they started.
741
00:45:43,760 --> 00:45:45,200
Do you do this exercise?
742
00:45:45,200 --> 00:45:49,400
Do you go back and look at companies you did not invest in and maybe you didn't come across
743
00:45:49,400 --> 00:45:52,040
or you did and you passed on them?
744
00:45:52,040 --> 00:45:56,720
And then do you change your investment thesis to any extent and say if you get one of these
745
00:45:56,720 --> 00:46:01,320
or say if you get 10 of these companies?
746
00:46:01,320 --> 00:46:05,240
I would tell you, I don't do the exercise, but my partners definitely do the exercise
747
00:46:05,240 --> 00:46:07,240
for me because they send me the deals.
748
00:46:07,240 --> 00:46:08,500
You said no on this.
749
00:46:08,500 --> 00:46:10,040
Look at this billion dollar exit.
750
00:46:10,040 --> 00:46:11,680
So no, I'm kidding.
751
00:46:11,680 --> 00:46:12,680
They don't.
752
00:46:12,680 --> 00:46:14,120
Thankfully we have a great partnership.
753
00:46:14,120 --> 00:46:15,120
We don't do that.
754
00:46:15,120 --> 00:46:23,960
But I would say I do, I look at that from a, from a just an experiential intellectual
755
00:46:23,960 --> 00:46:24,960
perspective.
756
00:46:24,960 --> 00:46:27,920
I don't beat myself up about not making the investment.
757
00:46:27,920 --> 00:46:31,200
I mean, some of these ones that you're talking about, we had the opportunity to invest.
758
00:46:31,200 --> 00:46:35,160
I think if you stay fundamental to a thesis, some things just don't fit.
759
00:46:35,160 --> 00:46:37,880
And those, the ones that you hear about are the outliers.
760
00:46:37,880 --> 00:46:42,320
One thing I've learned when I got into investing, I mean, we look at 70, 80, a hundred deals
761
00:46:42,320 --> 00:46:43,320
a week, right?
762
00:46:43,320 --> 00:46:46,080
But you can't invest in all of them.
763
00:46:46,080 --> 00:46:50,720
And the ones that make the headlines are the ones that break away like that.
764
00:46:50,720 --> 00:46:56,040
But categorically, if it doesn't fit your thesis, then you'll make a mistake 99 times
765
00:46:56,040 --> 00:46:57,960
and have success once.
766
00:46:57,960 --> 00:47:03,040
And I think that's okay in venture if you've right sized your venture investments probably,
767
00:47:03,040 --> 00:47:07,160
you know, that one has a hundred billion exits, so to speak.
768
00:47:07,160 --> 00:47:11,760
It's fine that the 99 went to zero in venture math, but you better be pretty sure that you
769
00:47:11,760 --> 00:47:16,120
can do that on a repeated basis or there is no fun two or fun three or fun four.
770
00:47:16,120 --> 00:47:22,360
So I don't beat myself about the misses, but I do, I do look at them and I try to understand,
771
00:47:22,360 --> 00:47:26,800
you know, did I actually miss something or is this off thesis or this is a one off?
772
00:47:26,800 --> 00:47:30,400
Yeah, I'm really happy you said that.
773
00:47:30,400 --> 00:47:31,400
And I agree with it.
774
00:47:31,400 --> 00:47:34,640
You should not define your thesis chasing after Google.
775
00:47:34,640 --> 00:47:36,560
It was the 18th search engine.
776
00:47:36,560 --> 00:47:40,860
If you decided this wasn't for you after the 16th one, you would have missed out.
777
00:47:40,860 --> 00:47:47,040
So it's something you just have to have an infinite amount of money to pull off, I feel.
778
00:47:47,040 --> 00:47:48,040
Yeah.
779
00:47:48,040 --> 00:47:49,400
I mean, a lot of these businesses, you know, it's interesting.
780
00:47:49,400 --> 00:47:54,880
We've made an investment in a company called Stampede, which is a novel movie studio.
781
00:47:54,880 --> 00:48:02,800
This guy named Greg Silverman, who was the producer manager at Warner Brothers for 20
782
00:48:02,800 --> 00:48:06,160
years, super successful, highest grossing producer of all time.
783
00:48:06,160 --> 00:48:09,920
He did Harry Potter series, Batman, Hangover.
784
00:48:09,920 --> 00:48:12,040
This guy, I mean, this is the guy.
785
00:48:12,040 --> 00:48:19,040
We ran an exercise at our annual meeting last month where he had a grid of seven by seven
786
00:48:19,040 --> 00:48:23,000
movies, which were script titles that were pitched to him.
787
00:48:23,000 --> 00:48:29,760
And we were supposed to pick based on, you know, it was a British kid who is a wizard
788
00:48:29,760 --> 00:48:36,600
who lives below a stairwell and has plays at this school that's, you know, whatever.
789
00:48:36,600 --> 00:48:38,720
And everyone's like, absolutely would never do that.
790
00:48:38,720 --> 00:48:39,720
Right.
791
00:48:39,720 --> 00:48:40,720
It was Harry Potter.
792
00:48:40,720 --> 00:48:44,280
And so it was interesting when you go through what they, you know, his trade craft and his
793
00:48:44,280 --> 00:48:45,840
discipline of picking these movies.
794
00:48:45,840 --> 00:48:49,240
I mean, he can obviously pick winners.
795
00:48:49,240 --> 00:48:52,640
The skill set to pick, I mean, he even said it in our meeting.
796
00:48:52,640 --> 00:48:54,040
We get lucky sometimes, right?
797
00:48:54,040 --> 00:48:56,400
Like there are outliers to the Harry Potter.
798
00:48:56,400 --> 00:49:01,360
He picked he was everyone had rejected that every studio had rejected the books before,
799
00:49:01,360 --> 00:49:05,580
you know, and now look at the one of the great biggest grossing franchises of all time.
800
00:49:05,580 --> 00:49:10,800
So I think you could learn from it, but I don't like you said, I don't we don't I try
801
00:49:10,800 --> 00:49:13,800
not to define by what I consider mistakes.
802
00:49:13,800 --> 00:49:19,040
Do you think you learn more from your successes than your failures?
803
00:49:19,040 --> 00:49:20,320
And I will give my answer.
804
00:49:20,320 --> 00:49:21,320
Yes.
805
00:49:21,320 --> 00:49:23,840
I have learned more from my successes.
806
00:49:23,840 --> 00:49:25,960
And I know this is not the popular answer.
807
00:49:25,960 --> 00:49:32,000
I have learned humility and introspection and reflection from my failures.
808
00:49:32,000 --> 00:49:36,600
But in terms of decision making, I feel like I've learned more from successes.
809
00:49:36,600 --> 00:49:38,800
Yeah, I would agree with that.
810
00:49:38,800 --> 00:49:40,120
I mean, I think I've learned more from the success.
811
00:49:40,120 --> 00:49:45,000
But I think what I've learned from failures is how to be more successful, not necessarily
812
00:49:45,000 --> 00:49:47,880
learn a task or a skill or an idea.
813
00:49:47,880 --> 00:49:54,760
It was, you know, we had we invested in a company where the founder had, you know, we
814
00:49:54,760 --> 00:49:59,960
should have done better due diligence on the founder and his background, etc, etc.
815
00:49:59,960 --> 00:50:03,040
So now, you know, we run a background check on everybody before we make it like those
816
00:50:03,040 --> 00:50:04,040
kinds of things.
817
00:50:04,040 --> 00:50:07,760
They're operational infrastructure things that I think I've learned over the years.
818
00:50:07,760 --> 00:50:12,480
Investor, you know, I've never done a reverse merger IPO with an Israeli shell company.
819
00:50:12,480 --> 00:50:16,560
Well, now we've sort of done it and we understand how to like those kinds of things from those
820
00:50:16,560 --> 00:50:20,760
kinds of failures where we ended up in a situation that we had to navigate out of.
821
00:50:20,760 --> 00:50:25,080
We've learned something that now for other companies that we have, we have a better toolbox
822
00:50:25,080 --> 00:50:27,960
of saying, hey, this is one of the possibilities now.
823
00:50:27,960 --> 00:50:31,640
So I don't for me, it's not been so cut and dry of the conventional, you know, is your
824
00:50:31,640 --> 00:50:34,440
success versus failure learning.
825
00:50:34,440 --> 00:50:37,840
And you know, you teach this to your kids or they tell you to teach it to your kids
826
00:50:37,840 --> 00:50:41,680
that your kids fail so that they can understand success kind of thing.
827
00:50:41,680 --> 00:50:45,220
It's so different, I think, in investing and understanding how this kind of stuff works,
828
00:50:45,220 --> 00:50:51,560
because there's a mechanistic component to just investing, like how to read a term sheet
829
00:50:51,560 --> 00:50:56,760
and how to do a deal and IPO and this and caps and all of these things that come into
830
00:50:56,760 --> 00:51:01,040
liquidity preference, how it all works, that plays such an important role in success or
831
00:51:01,040 --> 00:51:02,040
failure.
832
00:51:02,040 --> 00:51:03,560
You can have something that's very successful.
833
00:51:03,560 --> 00:51:07,440
We're looking at a company right now that they're recapping the company.
834
00:51:07,440 --> 00:51:09,920
We looked a few years ago, it was too rich for our blood.
835
00:51:09,920 --> 00:51:14,880
Now they're recapping the company where the founders have ended up with 1% of the company
836
00:51:14,880 --> 00:51:19,120
after two rounds and that everyone's realized that there is no company unless we recap the
837
00:51:19,120 --> 00:51:21,280
company and give the founders back 30% equity.
838
00:51:21,280 --> 00:51:24,120
You know, that kind of thing is just an experiential thing.
839
00:51:24,120 --> 00:51:26,040
It's got nothing to do with no one fail.
840
00:51:26,040 --> 00:51:29,560
It's just the fundraising went in a way that there were so many people involved that the
841
00:51:29,560 --> 00:51:33,440
cap table got completely squeezed down that these guys sold all their equity out and now
842
00:51:33,440 --> 00:51:34,760
there's no motivation to grow a company.
843
00:51:34,760 --> 00:51:36,160
But the company is good.
844
00:51:36,160 --> 00:51:40,080
So there's investors who are interested in recapping the company.
845
00:51:40,080 --> 00:51:47,000
Okay, let's talk about hiring employees, co-founders and finding a partner.
846
00:51:47,000 --> 00:51:53,040
The lens I want you to answer this question through is Danny Kahneman's decision-making
847
00:51:53,040 --> 00:51:56,040
framework.
848
00:51:56,040 --> 00:52:01,320
I used to hire based on intuition and that was the wrong thing for me.
849
00:52:01,320 --> 00:52:08,580
I've made some terrible mistakes because how do you approach hiring employees and looking
850
00:52:08,580 --> 00:52:14,680
for a co-founder, do you have a structured approach and how do you factor in intuition?
851
00:52:14,680 --> 00:52:20,080
Yeah, I mean, I think co-founder is a very different whole thing, right?
852
00:52:20,080 --> 00:52:24,120
I mean, co-founder is there's a personal component, a professional component, an intellectual
853
00:52:24,120 --> 00:52:25,680
component and a financial component.
854
00:52:25,680 --> 00:52:31,240
I mean, it's very different and that for me and all of the things that I've done where
855
00:52:31,240 --> 00:52:35,960
I've had a co-founder or a partner in a business has been we were friends first and then we
856
00:52:35,960 --> 00:52:38,120
moved into a business relationship.
857
00:52:38,120 --> 00:52:44,520
And we've but very upfront built a business relationship with tax and blocks and tackles
858
00:52:44,520 --> 00:52:49,520
in the documents that shotgun clauses, whatever it was that we understand upfront that if
859
00:52:49,520 --> 00:52:53,200
we get into a fight, which everyone tells you don't do business with your friends, which
860
00:52:53,200 --> 00:52:57,900
I have done business with all my friends is we just build a way that there's a structure
861
00:52:57,900 --> 00:53:00,480
that no one gets into a fight and everyone understands how it's going to be.
862
00:53:00,480 --> 00:53:03,660
So I think as a co-founder, it's a very different exercise.
863
00:53:03,660 --> 00:53:09,880
On the employee side, both my company, our fund, all of these other things, we've tried
864
00:53:09,880 --> 00:53:13,800
360 evaluations and neograms.
865
00:53:13,800 --> 00:53:19,240
There's a host of tools that you fill in these questions, all of this stuff.
866
00:53:19,240 --> 00:53:24,640
I personally have never had that much success with these orchestrated tools.
867
00:53:24,640 --> 00:53:29,300
I think they give you, if you have a limited time of assessment with somebody, they do
868
00:53:29,300 --> 00:53:34,840
give you insight that's very valuable in terms of are they a high performer?
869
00:53:34,840 --> 00:53:36,760
Are they obsessive compulsive?
870
00:53:36,760 --> 00:53:40,480
Whatever these factors that you're looking for.
871
00:53:40,480 --> 00:53:45,160
But I think if you spend enough time with somebody that all of those things as an employer,
872
00:53:45,160 --> 00:53:47,780
as a partner, we're able to garner.
873
00:53:47,780 --> 00:53:49,640
And so that's what we try to focus on.
874
00:53:49,640 --> 00:53:53,840
We try to spend a good amount of time with someone upfront and then to a certain extent
875
00:53:53,840 --> 00:53:56,360
hope for the best.
876
00:53:56,360 --> 00:54:00,720
I've been proven wrong on lots of the 360 evaluations that we've done where the thing
877
00:54:00,720 --> 00:54:04,920
says this person is awesome and they turn out to be awful and vice versa.
878
00:54:04,920 --> 00:54:08,320
We've had people who we thought there's no way this person could succeed and then they're
879
00:54:08,320 --> 00:54:11,680
the most successful person on whatever entity it was.
880
00:54:11,680 --> 00:54:12,680
Okay.
881
00:54:12,680 --> 00:54:13,960
Do you have time for one more question?
882
00:54:13,960 --> 00:54:14,960
If not, we can...
883
00:54:14,960 --> 00:54:15,960
I do.
884
00:54:15,960 --> 00:54:16,960
Yeah.
885
00:54:16,960 --> 00:54:17,960
Let's talk about...
886
00:54:17,960 --> 00:54:23,920
And I had questions for each one of the four pillars and I think maybe in the next round
887
00:54:23,920 --> 00:54:26,040
we'll get to it.
888
00:54:26,040 --> 00:54:28,520
I'm already marking down the next round by the way.
889
00:54:28,520 --> 00:54:33,680
Let's talk about AI and explainability.
890
00:54:33,680 --> 00:54:36,240
I talked to this about Amit from Tao Ventures.
891
00:54:36,240 --> 00:54:37,240
I don't know if you know him.
892
00:54:37,240 --> 00:54:38,240
I do.
893
00:54:38,240 --> 00:54:40,160
We're invested in a company together actually.
894
00:54:40,160 --> 00:54:41,160
Okay.
895
00:54:41,160 --> 00:54:42,160
Yeah.
896
00:54:42,160 --> 00:54:44,560
And he gave an amazing answer.
897
00:54:44,560 --> 00:54:46,360
So the pressure is on Amit.
898
00:54:46,360 --> 00:54:47,360
All right.
899
00:54:47,360 --> 00:54:53,840
AI and explainability in the sense of right now the regulatory framework in healthcare
900
00:54:53,840 --> 00:55:00,600
requires us to an extent to understand what the AI is doing, to understand the networks
901
00:55:00,600 --> 00:55:04,320
or the processes behind the outcomes.
902
00:55:04,320 --> 00:55:07,440
When do we let go of that need for explainability?
903
00:55:07,440 --> 00:55:13,840
If the AI is providing amazing outcomes, maybe outcomes better than humans, when do we say,
904
00:55:13,840 --> 00:55:20,360
okay, let us let this algorithm do its job, provide us with care, with decisions on when
905
00:55:20,360 --> 00:55:25,240
to operate, when not to operate, what drugs to use even, what diagnoses, and maybe we
906
00:55:25,240 --> 00:55:27,640
don't even answer the diagnoses.
907
00:55:27,640 --> 00:55:30,760
At what point do we let go of that need for explainability?
908
00:55:30,760 --> 00:55:34,840
Because by not doing so, we're limiting the scope of AI, I feel.
909
00:55:34,840 --> 00:55:35,840
Yeah.
910
00:55:35,840 --> 00:55:40,320
So interestingly, like radiology has been on the forefront of this, right?
911
00:55:40,320 --> 00:55:44,480
And so through our clinical trial company, we did the approvals for a lot of these AI
912
00:55:44,480 --> 00:55:45,480
products.
913
00:55:45,480 --> 00:55:51,160
The FDA as a regulatory body has already given blessing on not knowing how the AI works.
914
00:55:51,160 --> 00:55:55,520
So in a compositional neural network, in a pure CNN, it truly is a black box, right?
915
00:55:55,520 --> 00:55:57,640
So it's input in, input out, back test.
916
00:55:57,640 --> 00:56:00,960
So no one understands how, I mean, there is no understanding of how the black box works
917
00:56:00,960 --> 00:56:03,880
per se, but those algorithms are approved.
918
00:56:03,880 --> 00:56:09,720
So we have FDA approval for several algorithms that nobody knows how they work, quote unquote,
919
00:56:09,720 --> 00:56:10,720
right?
920
00:56:10,720 --> 00:56:11,720
Oh, perfect.
921
00:56:11,720 --> 00:56:17,400
So AI exists, and the FDA is moving through this in terms of defining, there's a whole
922
00:56:17,400 --> 00:56:18,600
host of secondary.
923
00:56:18,600 --> 00:56:24,720
So AI is going through this evolution of sort of what I call AI 1.0, which has been traditionally
924
00:56:24,720 --> 00:56:28,280
sort of detection technology, and it's not controversial, right?
925
00:56:28,280 --> 00:56:30,660
Is there a mass on this picture?
926
00:56:30,660 --> 00:56:33,200
Is there an abnormality in the CBC?
927
00:56:33,200 --> 00:56:35,160
Is there whatever it may be?
928
00:56:35,160 --> 00:56:36,480
It's not controversial in understanding.
929
00:56:36,480 --> 00:56:40,100
It's a detection technology, and there's been detection technology for a long time.
930
00:56:40,100 --> 00:56:41,560
No one has an issue with that.
931
00:56:41,560 --> 00:56:45,880
The detection is getting better, and the detection is getting to a level where we're asymptotic
932
00:56:45,880 --> 00:56:50,480
and where you cannot, as computing power goes to, the cost of computing goes to zero, this
933
00:56:50,480 --> 00:56:54,160
gets better and you can detect better and be more holistic about it.
934
00:56:54,160 --> 00:56:58,840
This next generation of AI is, which I don't think we're at, which, and I'm going to get
935
00:56:58,840 --> 00:57:02,920
to your point, is sort of where there's an interpretation of what is detected.
936
00:57:02,920 --> 00:57:04,920
So you're making an evaluation.
937
00:57:04,920 --> 00:57:08,120
And so for example, you find a mass on a mammogram.
938
00:57:08,120 --> 00:57:14,440
There's a company that has a heat map that it takes and ingests your BRCA, it ingests
939
00:57:14,440 --> 00:57:18,320
your family history, it ingests your diet, a whole bunch of other risk factors to give
940
00:57:18,320 --> 00:57:22,480
an assessment of whether or not that mass is going to turn into a cancer.
941
00:57:22,480 --> 00:57:25,280
1.0 tells you, is it a cancer or not?
942
00:57:25,280 --> 00:57:30,240
And if it's not, 2.0 tells you, based on all these other risk factors, it's going to become
943
00:57:30,240 --> 00:57:31,380
a cancer.
944
00:57:31,380 --> 00:57:35,600
So that's sort of 2.0, and I think 3.0 is what you're talking about, where it's a true
945
00:57:35,600 --> 00:57:36,600
decision maker.
946
00:57:36,600 --> 00:57:42,160
I think as a society, we probably don't want computers to make that decision, open AI or
947
00:57:42,160 --> 00:57:43,720
all the money, fear and all that.
948
00:57:43,720 --> 00:57:51,360
But I think it's inevitable that a component of what we do will become, and AI will adjunct
949
00:57:51,360 --> 00:57:52,360
what we do.
950
00:57:52,360 --> 00:57:54,880
And imaging is a great example, right?
951
00:57:54,880 --> 00:58:01,120
I think in 2022, as long as I am a licensed physician who is trained, who's willing to
952
00:58:01,120 --> 00:58:07,240
sign off on something, I can use the AI to adjunct and augment what I do.
953
00:58:07,240 --> 00:58:10,800
There's an algorithm that can find a rib fracture on a CT scan.
954
00:58:10,800 --> 00:58:13,880
Does anyone in the world have a problem with me using that algorithm?
955
00:58:13,880 --> 00:58:18,600
Absolutely not, as long as the algorithm detects and I say, I agree, and that's a rib fracture.
956
00:58:18,600 --> 00:58:23,080
So that, I think we're there, and that's where we are today.
957
00:58:23,080 --> 00:58:28,680
So the question becomes is, as we evolve, are we okay with AI making the ultimate decision?
958
00:58:28,680 --> 00:58:33,120
And then the constituents there are going to be, again, the provider, the payer, and
959
00:58:33,120 --> 00:58:34,720
the patient.
960
00:58:34,720 --> 00:58:42,680
I think the patient reflects on society, FDA, everybody else to make sure, just like the
961
00:58:42,680 --> 00:58:48,560
Consumer Protection Bureau protects consumers from ovens going on fire, right?
962
00:58:48,560 --> 00:58:52,200
We as a society expect these regulatory bodies to protect us.
963
00:58:52,200 --> 00:58:53,800
So I don't think the patients make a decision.
964
00:58:53,800 --> 00:58:58,240
The patients say, if the FDA says it's okay, it's okay, as we've done with almost everything
965
00:58:58,240 --> 00:58:59,680
else.
966
00:58:59,680 --> 00:59:04,280
The providers, I think as long as they're getting an economic benefit or do not lose
967
00:59:04,280 --> 00:59:07,400
an economic benefit, are absolutely fine using it.
968
00:59:07,400 --> 00:59:12,440
So in my rib fracture example, if insurance is willing to pay for me to use the rib fracture
969
00:59:12,440 --> 00:59:14,800
algorithm, I have no problem using it.
970
00:59:14,800 --> 00:59:16,920
Makes me a better doctor, better diagnostician.
971
00:59:16,920 --> 00:59:20,040
I miss less fractures all day long.
972
00:59:20,040 --> 00:59:23,640
So it comes down to the payer, right?
973
00:59:23,640 --> 00:59:26,360
And it comes down to money, which is what all of this comes down to.
974
00:59:26,360 --> 00:59:28,920
So the payer says, why am I willing to pay for this?
975
00:59:28,920 --> 00:59:32,760
The only reason I'm willing to pay for this, honestly, right, if we're true to ourselves,
976
00:59:32,760 --> 00:59:35,600
is that it reduces my cost of providing care.
977
00:59:35,600 --> 00:59:39,160
So if we go back to my rib fracture example, and I use this specifically, if you have a
978
00:59:39,160 --> 00:59:43,720
rib fracture on a CT scan that's not significantly displaced, you know what we tell you to do?
979
00:59:43,720 --> 00:59:45,960
Take two Advil and we'll call you in the morning, right?
980
00:59:45,960 --> 00:59:47,680
There's no treatment for that per se.
981
00:59:47,680 --> 00:59:49,880
I'm not talking about a flail chest or a pneumothorax.
982
00:59:49,880 --> 00:59:52,500
I'm just talking about a non-displaced rib fracture.
983
00:59:52,500 --> 00:59:56,200
So at the end of the day for the payer, did it really matter if I found that rib fracture
984
00:59:56,200 --> 00:59:58,280
probably not, right?
985
00:59:58,280 --> 01:00:02,160
Academically, for us, it matters that we don't miss a finding.
986
01:00:02,160 --> 01:00:03,160
For the patient, it matters.
987
01:00:03,160 --> 01:00:06,440
Now they have an explanation for their right side of chest pain.
988
01:00:06,440 --> 01:00:11,320
But the payer, and this at some point was supposition, now it's playing out because
989
01:00:11,320 --> 01:00:16,720
I've seen many, many, many AI companies that have closed shop because they went to the
990
01:00:16,720 --> 01:00:18,640
payer and the payer said no.
991
01:00:18,640 --> 01:00:20,820
They went to the patient and the patient said no.
992
01:00:20,820 --> 01:00:24,500
They went to the hospital, the hospital said no, we're not paying for this.
993
01:00:24,500 --> 01:00:26,800
And they have to close shop because they couldn't find a payer.
994
01:00:26,800 --> 01:00:30,920
So I think that's what ends up driving some of this stuff at the end of the day is, is
995
01:00:30,920 --> 01:00:37,480
there a economic benefit to that algorithm independent of, lots of time there's a clinical
996
01:00:37,480 --> 01:00:41,020
benefit and there's no question there's a clinical benefit.
997
01:00:41,020 --> 01:00:43,520
But that's not what the driver of the technology is.
998
01:00:43,520 --> 01:00:45,740
The driver is who's going to pay for it.
999
01:00:45,740 --> 01:00:51,120
So that's experientially what I've learned as an investor is like when we have these
1000
01:00:51,120 --> 01:00:53,760
companies that come, we say, who's going to pay for this?
1001
01:00:53,760 --> 01:00:56,120
Oh, well, we'll figure that out later.
1002
01:00:56,120 --> 01:00:57,120
Not investing in your company.
1003
01:00:57,120 --> 01:01:02,640
Or I'm going to get a CPT code and I'm going to get reimbursement for this.
1004
01:01:02,640 --> 01:01:03,640
Not investing in that.
1005
01:01:03,640 --> 01:01:07,880
You have not been through the system because the payer is not going to pay for that unless
1006
01:01:07,880 --> 01:01:09,760
you can prove benefit.
1007
01:01:09,760 --> 01:01:16,440
How far are we from the AI being the provider, at least for certain verticals like, you know,
1008
01:01:16,440 --> 01:01:18,960
UTI and birth control refills?
1009
01:01:18,960 --> 01:01:19,960
Yeah.
1010
01:01:19,960 --> 01:01:23,680
I mean, I don't know if you've used chat GPT yet, but I haven't.
1011
01:01:23,680 --> 01:01:25,200
Yeah, I mean, just type in.
1012
01:01:25,200 --> 01:01:26,200
I got a cold one.
1013
01:01:26,200 --> 01:01:27,560
I mean, chat GPT is amazing.
1014
01:01:27,560 --> 01:01:33,120
So AI inner sort of generational AI, I think, is at that level now.
1015
01:01:33,120 --> 01:01:34,120
So I think we're there.
1016
01:01:34,120 --> 01:01:40,960
I mean, if it's algorithmic algorithmic treatment, which is in essence what you know, there's
1017
01:01:40,960 --> 01:01:44,600
a whole host of companies doing asynchronous care, right?
1018
01:01:44,600 --> 01:01:50,240
You have an app, you log on, you say, I've got a cough, I've got a fever, I've got green
1019
01:01:50,240 --> 01:01:52,840
sputum, I've got shortness of breath.
1020
01:01:52,840 --> 01:01:55,120
Pretty high chance you got a pneumonia.
1021
01:01:55,120 --> 01:01:58,360
And if it's hurting on the right side, it's in the right lower lobe, right?
1022
01:01:58,360 --> 01:02:03,260
So that asynchronous data capture, they then send you for a chest x-ray and some labs,
1023
01:02:03,260 --> 01:02:05,120
and then they get that result.
1024
01:02:05,120 --> 01:02:07,400
And then they, you know, you get antibiotics.
1025
01:02:07,400 --> 01:02:10,800
There isn't a need for a level five or an ND visit.
1026
01:02:10,800 --> 01:02:13,640
I mean, you can go see a PA or maybe an NP if you need to.
1027
01:02:13,640 --> 01:02:19,360
But a lot, you know, for the most part, that visit doesn't add AI and even chat GPT, which
1028
01:02:19,360 --> 01:02:24,520
sounds crazy, but conversational AI on asynchronous data capture and treatment, I think is there
1029
01:02:24,520 --> 01:02:25,520
today.
1030
01:02:25,520 --> 01:02:29,160
Now it goes back to the same problem of, you know, again, in the money, talking about the
1031
01:02:29,160 --> 01:02:33,480
money again, there's obviously a, you know, the litiginous part of it.
1032
01:02:33,480 --> 01:02:35,480
There's, you know, we worry about all that.
1033
01:02:35,480 --> 01:02:37,000
What happens when the AI makes a mistake?
1034
01:02:37,000 --> 01:02:38,000
Who do you sue?
1035
01:02:38,000 --> 01:02:39,000
All that kind of stuff.
1036
01:02:39,000 --> 01:02:45,480
But I think as it augments to the position in 2022, it's worth, I mean, there is capability
1037
01:02:45,480 --> 01:02:48,280
there and radiology has been one of those places where it's been first.
1038
01:02:48,280 --> 01:02:53,400
I mean, we augment what we do in mammography with cat with AI, right?
1039
01:02:53,400 --> 01:02:57,560
We bring up the mammogram, we look at it, we hit a button, the algorithm will highlight
1040
01:02:57,560 --> 01:02:59,240
a mass recalcitration.
1041
01:02:59,240 --> 01:03:02,960
We use that and use that to make a better interpretation.
1042
01:03:02,960 --> 01:03:07,280
So I think for the foreseeable future, it's AI augmenting the physician.
1043
01:03:07,280 --> 01:03:10,920
There is a day where I think it crosses over, but it has to get to a level of sensitivity
1044
01:03:10,920 --> 01:03:18,280
and specificity where it ensures providers feel comfortable that the system isn't going
1045
01:03:18,280 --> 01:03:19,280
to screw you.
1046
01:03:19,280 --> 01:03:20,280
Okay, perfect.
1047
01:03:20,280 --> 01:03:23,080
Amit, thanks so much for taking the time to be here.
1048
01:03:23,080 --> 01:03:24,080
Yeah, absolutely.
1049
01:03:24,080 --> 01:03:26,960
I had an amazing time and we'll have to do it again.
1050
01:03:26,960 --> 01:03:30,920
Yeah, I appreciate the time and I'm excited about what you guys are doing and love to help
1051
01:03:30,920 --> 01:03:35,760
out with the forum and as people sort of make their way through investments, you know, feel
1052
01:03:35,760 --> 01:03:36,760
free to reach out.
1053
01:03:36,760 --> 01:03:37,760
I'm happy to help in any way.
1054
01:03:37,760 --> 01:03:38,760
Thanks.
1055
01:03:38,760 --> 01:03:41,760
Amit.
00:00:00,000 --> 00:00:03,000
Hi everyone, thanks so much for joining me today.
2
00:00:03,000 --> 00:00:05,840
Today I'm talking to Amit Mehta.
3
00:00:05,840 --> 00:00:10,280
He's an interventional radiologist and a general partner at Builders VC.
4
00:00:10,280 --> 00:00:15,180
Builders VC is a $450 million venture capital firm.
5
00:00:15,180 --> 00:00:18,880
They invest across all verticals, including healthcare.
6
00:00:18,880 --> 00:00:23,200
I hope you guys enjoyed the conversation with Amit as much as I did.
7
00:00:23,200 --> 00:00:26,440
Amit, thanks so much for coming on the podcast.
8
00:00:26,440 --> 00:00:28,960
Really looking forward to this call.
9
00:00:28,960 --> 00:00:34,760
To start, if you want to give us a brief introduction and then we'll get right into it.
10
00:00:34,760 --> 00:00:35,760
Sure.
11
00:00:35,760 --> 00:00:38,560
So, I grew up in Canada.
12
00:00:38,560 --> 00:00:45,400
I spent my childhood in Toronto, went to school in Canada and then saw some need for some
13
00:00:45,400 --> 00:00:51,160
technology as I was moving through medical school and figured that I couldn't do it there
14
00:00:51,160 --> 00:00:52,160
in Canada.
15
00:00:52,160 --> 00:00:58,960
So, for residency, decided to come to the US and work specifically on some specific
16
00:00:58,960 --> 00:00:59,960
problems.
17
00:00:59,960 --> 00:01:05,840
So, I trained through the Harvard system at Mass General, did essentially all my training
18
00:01:05,840 --> 00:01:12,320
there, fellowship and then ran a lab, research lab there for a few years while I was doing
19
00:01:12,320 --> 00:01:15,240
residency and did a few other things that were of interest.
20
00:01:15,240 --> 00:01:20,480
But during that time, got interested in investing and startup and got involved in that whole
21
00:01:20,480 --> 00:01:22,600
ecosystem there.
22
00:01:22,600 --> 00:01:31,600
Once I finished training, I had a thesis to run that lab there but then decided, had spent
23
00:01:31,600 --> 00:01:36,760
an infinitesimally small amount of money on my medical school education compared to my
24
00:01:36,760 --> 00:01:38,400
cohorts in the US and felt bad.
25
00:01:38,400 --> 00:01:41,960
So, I said, I'm going to come back to Canada and not contribute to the brain drain.
26
00:01:41,960 --> 00:01:46,760
So, moved back to Canada and worked in Canada for a couple of years, again, trying to move
27
00:01:46,760 --> 00:01:51,040
forward some of these ideas that I was working on in telemedicine and teleradiology and all
28
00:01:51,040 --> 00:01:53,040
of this kind of stuff.
29
00:01:53,040 --> 00:01:58,320
In that process, my wife who was from LA hated the cold and said, we got to move somewhere
30
00:01:58,320 --> 00:02:00,040
warm.
31
00:02:00,040 --> 00:02:05,320
And so, in that journey, moved back to the US and kept going on all the things that I
32
00:02:05,320 --> 00:02:06,320
was doing.
33
00:02:06,320 --> 00:02:13,040
Tell me a bit more about what tech did you foresee that was not feasible in Canada and
34
00:02:13,040 --> 00:02:16,280
you hinted towards teleradiology and telemedicine.
35
00:02:16,280 --> 00:02:22,560
And was it not feasible because of reimbursement issues, regulatory issues or something else?
36
00:02:22,560 --> 00:02:24,040
Yes.
37
00:02:24,040 --> 00:02:28,080
Basically, all of the above.
38
00:02:28,080 --> 00:02:32,680
So conceptually, what I was working on when I was doing residency and fellowship was a
39
00:02:32,680 --> 00:02:37,180
combination of telemedicine but also applying telemedicine and teleradiology into the clinical
40
00:02:37,180 --> 00:02:39,240
trial sphere.
41
00:02:39,240 --> 00:02:41,800
And that didn't work in Canada for a couple of reasons.
42
00:02:41,800 --> 00:02:46,240
One, I mean, there was no concept of telemedicine from both a technologic infrastructure standpoint
43
00:02:46,240 --> 00:02:49,680
nor from a reimbursement standpoint.
44
00:02:49,680 --> 00:02:55,160
There was no drive to even innovate in that space, venture and startup and all of which
45
00:02:55,160 --> 00:03:00,320
now is very robust in Canada through Mars and through BDC and a lot of the entities
46
00:03:00,320 --> 00:03:07,240
that as a VC now, those entities are actually limited partners in our funds.
47
00:03:07,240 --> 00:03:09,000
There was none of that.
48
00:03:09,000 --> 00:03:11,120
This was 15 years ago.
49
00:03:11,120 --> 00:03:17,320
And so I tried to push this agenda of what at the time I thought was sort of revolutionary
50
00:03:17,320 --> 00:03:21,400
in terms of bringing care to underserviced areas, which was a big problem in Canada,
51
00:03:21,400 --> 00:03:22,400
right?
52
00:03:22,400 --> 00:03:24,960
Northern Ontario and lots of other places.
53
00:03:24,960 --> 00:03:27,080
There was just no appetite for it.
54
00:03:27,080 --> 00:03:31,280
And the extension of that was what I initially had dreamt of was working on a clinical trial
55
00:03:31,280 --> 00:03:37,800
company where we had some technology and some ideas around making clinical trials more efficient
56
00:03:37,800 --> 00:03:43,160
and subsequently, several years later, did start that company, ran that and then we sold
57
00:03:43,160 --> 00:03:45,440
that company last year to a public.
58
00:03:45,440 --> 00:03:50,760
So in the end, it turned out and there was fruition to all the goals, but in Canada,
59
00:03:50,760 --> 00:03:53,160
I just didn't feel like I could get it done.
60
00:03:53,160 --> 00:03:57,880
Have you seen, and I've had similar experiences with my startup in Canada and talking to the
61
00:03:57,880 --> 00:04:04,080
Ministry of Health here as their primary goal is being reelected and nothing else.
62
00:04:04,080 --> 00:04:11,160
Have you seen any changes now and if you were a resident or in med school now, would you
63
00:04:11,160 --> 00:04:14,680
have stayed in Canada or do you think things are more or less the same still?
64
00:04:14,680 --> 00:04:18,200
No, I think it's done a complete 180 and it's completely changed.
65
00:04:18,200 --> 00:04:24,420
I mean, we're sourcing a lot of our deals on the venture side from Canada.
66
00:04:24,420 --> 00:04:29,720
We have a mandate because these Canadian entities, Alberta Enterprise and a few others are LPs
67
00:04:29,720 --> 00:04:30,720
in our fund.
68
00:04:30,720 --> 00:04:33,960
We have a Canadian mandate that we need to spend a certain amount of money in Canada
69
00:04:33,960 --> 00:04:37,160
and we don't have trouble finding deals.
70
00:04:37,160 --> 00:04:42,000
So I think that entire innovation ecosystem has completely blossomed from the time that
71
00:04:42,000 --> 00:04:47,320
I was there and the difficulty what I had in terms of just the whole life cycle of a
72
00:04:47,320 --> 00:04:52,000
startup from fundraising to infrastructure to human capital.
73
00:04:52,000 --> 00:04:53,600
I just don't see that happening now.
74
00:04:53,600 --> 00:04:58,240
I mean, it's not, I don't think it's Silicon Valley, but it's also not as difficult it
75
00:04:58,240 --> 00:05:00,840
was when it was when I was doing it.
76
00:05:00,840 --> 00:05:02,960
Okay, yeah, that's good to hear.
77
00:05:02,960 --> 00:05:05,400
Let's go back to your childhood, Ahmed.
78
00:05:05,400 --> 00:05:10,960
Let's go back to when you were about 10, 15, maybe in high school.
79
00:05:10,960 --> 00:05:13,440
What did you want to be then?
80
00:05:13,440 --> 00:05:17,320
And once you were in med school, did you, most people in med school think they're going
81
00:05:17,320 --> 00:05:21,280
to be a doctor forever, as did I.
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When did that change for you?
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And did you say, okay, this isn't enough for me and I want to do something else or something
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more?
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I always wanted to be a doctor.
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I think I grew up in a family with physicians and all of the rest of, you know, typical
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sort of immigrant story, but I had a very, I think an interest in technology and a technological
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bent in terms of tinkering and, you know, ran illegal bulletin boards out of my attic
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and got in trouble with my parents and all of that kind of stuff when I was a kid.
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And so I was at an interest in technology.
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And so I was driven towards a technologic field and it was more finding the right time
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to start working on those ideas as opposed to trying to generate the idea or is it something
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I want to work on?
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I had determined I wanted to work on it very early.
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It was just, you know, back then it wasn't cool to be 17 and start a company as it is
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now, if you're 30, it's not cool.
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You need to be 15 to start a company.
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So that dynamic was very different.
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It was hard to get taken seriously as a 17, 18 year old, you know, and I mean, you guys
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are in Canada, you're in Canada, the back of the, I mean, I did the two year university
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four year med school thing.
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And so on top of that, I was going into being, you know, medical school really young, like
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16, 17.
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So it was hard to get, it was hard to be taken seriously.
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But I had those ideas and I was always working on those ideas as I kind of progressed through
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the system.
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So medicine was sort of, it was the day job and work on going through medical school and
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the academic component of it, but was working on those things at my own time.
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Okay, perfect.
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And why did you decide to pick intervention radiology?
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Primarily, again, like I'm at a very tech bent.
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It was very, I think it was a combination of a couple of things.
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One is, you know, you say, there's so many experiences shape who you are.
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So like I was telling you, like I went to medical school very early.
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Like I remember taking a primary care rotation and just patients just were like, you're too
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young to be my doc.
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Like I just was young and so people didn't take me seriously.
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So that was sort of steered me away from patient facing things almost off the bat because of
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this sort of this discrimination on age to a certain extent.
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But I did have a very tech bent.
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And so I was looking for things that were very heavy in that.
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So it almost fed me towards surgical specialties off the bat.
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And as I got further, I realized that maybe I'm a little bit ADHD and that, you know,
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I like to move very quickly and efficiently.
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And so radiology was something that was like that one.
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It wasn't as patient facing as I didn't want completely not patient facing, which, you
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know, interventional reality still is patient interaction.
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It's not all interpretation, but it was less patient facing.
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It was tech oriented.
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I could innovate in that space and it was still it was a high volume of cases moving
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very quickly, which was very attuned to my personality.
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So I think I was kind of lucky to find that early on that I found something that fits
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my personality.
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I never went through that concentration of is this the right thing for me or is this
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the right specialty?
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Like I loved it from the beginning and I've always loved I mean, to this day, I still
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enjoy it.
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Okay, perfect.
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You've had a lot of different experiences in the past 10 years.
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I'm and you know, someone would look at the resume and say, I'm a doesn't stick with things
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to an extent is tell me a bit more about joining your most favorite experience and then your
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least favorite if you'd like to.
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And what made the decision to were you like, I'm here for this job.
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I'm going to take this company from point A to point B when it's a point B, I'm going
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to leave or what was the thought process behind that?
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Yeah, it's funny.
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I think my detractors would say the opposite, I stick with things too long.
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So a lot of these Yeah, interestingly, I probably doing too many things and doing all of them
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at the same time as opposed to doing one and letting it go.
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But you know, the most interesting thing I think is definitely all for me as always been
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is been venture and being a GP and a fund and investing and all of the cool ideas and
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things you think about and figuring out a process of how to be a good investor and how
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to work on that.
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I mean, absolutely, that's been it's been fun.
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And it's been the exposure is incredible.
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You get to see things and touch things and do things that just you don't get any other
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way.
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Interesting way I would tell you that the flip side of that probably and I wouldn't
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say this is the worst experience, but the most difficult has been starting and selling
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this company like it was eight years of, you know, it was 100 hour weeks just working,
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it was stressful.
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And you know, it was enjoyable to a certain extent for certain things.
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But at the same time, it was very stressful to running a company running a you know, being
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a physician doing venture like it was just probably a lot of things at the same time.
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But at the same rate, it was instrumental, I think, in in forming a foundation for me
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to be a better investor, you know, coming from an operator perspective, to becoming
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an investor is a very different mode than just trying to be a primary investor.
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You know, I mean, this morning, I spent, you know, three hours on calls going through with
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entrepreneurs looking at 2023 budgets and pro forma is an understanding how to work
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out, you know, how to run a pro forma to make sure that your cause doesn't exceed your revenue
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and that your human capital is being, you know, all of that only comes from operational
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experience.
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It's hard to get that unless you've seen hundreds and hundreds of things or you've spent time
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very focused and understanding that specific problem.
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And so it was an education by fire to a certain extent that I think has helped me as an investor
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Okay, perfect.
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A lot of people are looking at the rising interest rates, recession and kind of buckling
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down, keeping more money in cash, not deploying as much capital.
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You know, I look at public and private markets as two different entities.
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I don't even try and compare the two.
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What is your strategy moving over the next six or 12 months?
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Are you changing the way you look at startups?
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Are you looking for startups that are almost maybe revenue neutral and whereas before you
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would be have more laxity there?
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Is your investment thesis changing at all and are you deploying less or more capital
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over the next six or 12 months?
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So I mean, there's a personal component and then there's an institutional component, right?
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And I would say on the institutional side, we are a series A fund and a seed fund.
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And so what's just evolved in the venture landscape is sort of valuations more than anything else.
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I mean, we're still with the companies we were investing in already were in a situation
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where they were often were not that revenue positive.
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They were beyond proof of concept, beyond seed stage companies, but they had not hit
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that hockey stick of growth yet.
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So that hasn't changed.
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I mean, we're still investing at the same level and series.
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It's just some of the deal metrics have changed in terms of valuations, in terms of ownership
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or what we're doing for that company.
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Our stage size of check and involvement in the company has stayed the same as it was
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a year or two or five ago.
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So we're not, you know, there's just these, I think, you know, part of the benefit of
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now being older is that this is cyclical, right?
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And I've been through a couple of cycles of this now and understand that all we did really
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honestly be truthful with you is we told our companies that, you know, you should stockpile
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30 months, you know, going out into the fundraising environment in the next 12 to 18 months is
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going to be really difficult unless you are one of the winning companies.
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I mean, if you're a winning company, there is money in the system, venture, whatever
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you want to say that has to be deployed, right?
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By definition, funds work by deploying capital.
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So that capital is going to be deployed to the winners.
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And so if you're a winner, it should be okay, but if you're on the precipice of being a
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winner or you're not a winner, then you need to hoard cash now.
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It's not that we think you're a bad company.
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It's just your life cycle over the next 18 months is going to be very different than
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a year ago when everyone was falling all over themselves.
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We had deals that were valued at 100 X ARR.
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I mean, I haven't seen a deal like that in nine months.
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Like, I mean, if you try to sell a deal now at 100 X ARR, people will just laugh at you
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and be like, you know, good luck.
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So I think that's the biggest shift is be conservative and, you know, we all hope our
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companies are winners.
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So if they're a winner, it's great.
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We can help them raise money.
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But if they're not or their inflection point is going to be a little more difficult.
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Okay, perfect.
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Talk to me about your first LP.
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How long did it take to get that investment?
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And does it get much easier after the first LP?
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There's a few GPs with smaller funds who listen to this, and I think they'd be very interested
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in the answer.
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Contrary to what everyone else says, I find fundraising the most difficult thing in the
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world.
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I mean, every single meeting is a different minefield.
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So in essence, right, in venture, I mean, as well as personal probably trackers, if
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you've had a track record of great investments, it speaks for itself.
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And this is like when you run a company.
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You know, when there's sales, everyone's happy.
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When there's no sales, then all of the problems start to come up.
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And, you know, this person is not doing this and that person is not doing this or this
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infrastructure is broken.
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So in venture, if your funds are doing well and you have returned that follow up meeting
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with an LP to ask for a check for the next fund is very straightforward because so look,
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we returned you 5x on our last fund.
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It's almost a fait accompli.
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Like, why wouldn't you put money into this next fund?
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The trouble is when your funds are not doing well, and you're asking for re-ups on checks.
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That's when it's difficult.
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But my philosophy has always been, you know, and this is somewhat medical, you know, driven
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in medicine into that if you're not doing something well, then maybe you need to look
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at some other, you know, don't kill people, like maybe pick another surgical specialist
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or something like you need to you need to pivot.
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And so luckily, our funds have done very well from the inception.
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And so we, you know, going into these LPs is more of a relationship driven fundraise
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rather than trying to prove our economics, our DPI and our, you know, everything has
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been good.
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So we haven't had that issue.
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Okay, perfect.
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When I think about my past investments, when I look at companies, I'm looking to invest
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right now, I usually look at the level of conviction I have and the potential reward.
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And usually sometimes I may have a lower level of conviction, but I'm getting in at a cheap
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valuation and there's a high level of reward.
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Talk to me about, I'll ask you about your best or your favorite investment first and
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we'll talk about your least favorite next.
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What was your level of conviction?
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What was the balance between your level of conviction and a potential reward in your
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favorite investment and then your least favorite?
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Yeah, I mean, I think that's a pretty difficult question to answer from a VC perspective.
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The decision is multifactorial, right?
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There's a myriad of things that go into deciding whether you make an investment, whether it's,
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you know, of which the entrepreneur is very important, the total market is important,
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the product is important, fit, all of those things go into that decision.
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I would say I've never made an investment that I didn't have a hundred percent full
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conviction on.
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Whatever got me to that level of conviction was different probably every time.
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And there's ebbs and flows.
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And like I think, again, like I said, as you understand, there's cycles in this stuff,
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there's different things at different times that are applicable, especially in healthcare,
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right?
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Healthcare investing is probably to me is more difficult than some of the other disciplines
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just because it's so heterogeneous.
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There's multiple verticals, there's payers, there's providers, there's patients, there's
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a FinTech component, there's a tech component, there's, you know, applicability in the market,
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there's hospitals, ACOs, clinics, I mean, it goes on and on and on, right?
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And so it's always at the end of the day, it's always been a hundred percent conviction,
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but the conviction has been around different things.
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And that's dependent on the cycle we're in, you know, decreasing reimbursement rates,
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is there opportunity of FinTech opportunities in healthcare right now, as opposed to, I
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think, during COVID and the pandemic, there was a lot of opportunity for remote care and
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moving tertiary care outside of the hospital to the home, remote monitoring, IOT.
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So there's a different, the conviction comes around different elements of the opportunity
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at the time in the cycle we're at.
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Okay, perfect.
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Amit, would you rather have a life of many successes, but no major success?
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Or would you rather have a life similar to Vincent van Gogh's?
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He had massive, what we would call failures, was not recognized in his own life, you know,
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infamously famous now.
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Would you rather have Vincent van Gogh's life, a hard life, lots of failures, no success
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while you were living, or a life of many successes, but you're not known, and you don't change
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the world in any substantial capacity?
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Yeah, I mean, I don't think the human brain is probably not wired to enjoy failure.
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So I don't, you know, I think it'd probably be the former.
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Yes, obviously, success feels good.
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But success and failure, I think, again, are also probably very, it's a very individual
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term.
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And what one may, you know, if you have an exit out of your company for $50,000, is that
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successful versus someone who has a $50 million or a $500 million exit?
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Once you've had a $500 million exit, then your next exit needs to be $5 billion, or
307
00:19:01,520 --> 00:19:02,520
you weren't successful.
308
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You know, your next exit at $500K is not successful, right?
309
00:19:06,880 --> 00:19:10,680
So I think some of that is just shaped on your experience.
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And what I've done, you know, I've tried to build a career around three facets, right?
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So there's a medical career, an actual physical operating career, the investment career, and
312
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then the innovative or the operator career of starting a company, running a company,
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and tried to bring all three of those things together to optimize what I can do as an investor,
314
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as a physician, and as an operator for each of those.
315
00:19:33,840 --> 00:19:38,880
So I think, I feel like success has been different in each of those things, and failure has been
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in each of those things.
317
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Like, you know, our failure on the operating side is very different than failure on the
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investing side, which means we lost $15 million in investment.
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Failure on the operating side is that we couldn't motivate our salespeople to make enough sales.
320
00:19:50,800 --> 00:19:55,440
You know, the magnitude of importance of those things are very different as for me as an
321
00:19:55,440 --> 00:20:00,520
individual, but as in my responsibility in each of those entities, is probably of equal
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importance.
323
00:20:01,520 --> 00:20:07,240
So it's just very dependent on what lens you're looking at it from, but I would say I don't
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like, I mean, I don't like failure.
325
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So I'm going to go with success more than failure.
326
00:20:11,800 --> 00:20:13,560
Okay, perfect.
327
00:20:13,560 --> 00:20:19,000
What advice do you have for founders trying to sell to health systems right now?
328
00:20:19,000 --> 00:20:24,120
How much should they, a lot of founders that come to me, they focus too much on clinical
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ROI and not enough on immediate financial ROI, which I feel a lot of health systems,
330
00:20:32,000 --> 00:20:40,000
ACOs, family health teams are more focused on and decisions are made more on financial
331
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ROI.
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You have a lot more experience than I do.
333
00:20:42,760 --> 00:20:46,600
It's more of a selfish question for me and what advice I should give to my founders right
334
00:20:46,600 --> 00:20:47,600
now.
335
00:20:47,600 --> 00:20:51,360
What advice would you give to founders trying to sell into health systems right now?
336
00:20:51,360 --> 00:20:55,000
You know, I said the thing that I think is the hardest thing to do in the world is to
337
00:20:55,000 --> 00:20:56,000
raise money from LPs.
338
00:20:56,000 --> 00:21:00,960
Let me give you a very, very close second is to sell into a hospital system.
339
00:21:00,960 --> 00:21:07,820
So, you know, selling to a hospital system, the problem is the incentives are probably
340
00:21:07,820 --> 00:21:16,680
perverse and it's very difficult to understand what those are in that the driver for a hospital
341
00:21:16,680 --> 00:21:18,080
system may not be what you...
342
00:21:18,080 --> 00:21:27,320
If you are not a provider or been on the medical staff or a CMO or a CMIO, whatever it may
343
00:21:27,320 --> 00:21:33,960
be, you may not understand what the driver is for that hospital system, hospital administrator
344
00:21:33,960 --> 00:21:39,120
who, you know, not a popular thing to say, but as we all know, they seem to rotate every
345
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two months.
346
00:21:40,120 --> 00:21:41,360
There's a new hospital administrator, right?
347
00:21:41,360 --> 00:21:46,280
The velocity of change in the hospital administrator is incredible.
348
00:21:46,280 --> 00:21:52,680
So I would say try to focus on products that probably don't sell to the hospital first,
349
00:21:52,680 --> 00:21:57,440
but saw more of a large clinical need where the hospital is where you end up as your larger
350
00:21:57,440 --> 00:22:02,000
clients once you've established a base with whatever else it may be.
351
00:22:02,000 --> 00:22:03,960
So telemedicine is a good example.
352
00:22:03,960 --> 00:22:09,880
Telemedicine is very applicable to hospital interactions, but maybe start in another setting,
353
00:22:09,880 --> 00:22:13,520
both prove out your infrastructure, prove out your business model, prove out your finances,
354
00:22:13,520 --> 00:22:16,440
and then that's the bigger fish to go after.
355
00:22:16,440 --> 00:22:17,800
Okay, perfect.
356
00:22:17,800 --> 00:22:24,120
Yeah, I mean, A16Z recently released their report about the pay-vider model and their
357
00:22:24,120 --> 00:22:28,460
banking on BTC consumer health.
358
00:22:28,460 --> 00:22:32,320
Let's talk a bit about the reimbursement structures in healthcare.
359
00:22:32,320 --> 00:22:37,960
And then particularly, do you think healthcare should be profitable?
360
00:22:37,960 --> 00:22:41,060
If so, what parts of healthcare should be profitable?
361
00:22:41,060 --> 00:22:42,400
Should it be primary care?
362
00:22:42,400 --> 00:22:44,640
Should it be more acute care, hospital care?
363
00:22:44,640 --> 00:22:53,240
As it stands now, the most profitable parts of healthcare are cancer therapy, surgeries,
364
00:22:53,240 --> 00:22:56,880
which I think should be perhaps at least profitable.
365
00:22:56,880 --> 00:23:02,920
And I also think innovation in healthcare should be decoupled from delivery of healthcare.
366
00:23:02,920 --> 00:23:07,840
So I'd like to get your thoughts on innovation and delivery in healthcare.
367
00:23:07,840 --> 00:23:12,320
Should they be different financial systems and incentives for both and profitability
368
00:23:12,320 --> 00:23:13,320
in healthcare?
369
00:23:13,320 --> 00:23:16,960
Yeah, that's a very interesting question.
370
00:23:16,960 --> 00:23:21,720
So I've worked in the US system and the Canadian system, and we've done a lot of work in the
371
00:23:21,720 --> 00:23:22,840
UK system.
372
00:23:22,840 --> 00:23:28,840
So I've seen three very different models of healthcare, worked in two of them and worked
373
00:23:28,840 --> 00:23:30,880
very closely in the third.
374
00:23:30,880 --> 00:23:35,240
And so I will tell you, I think my personal opinion is there's probably no optimal system.
375
00:23:35,240 --> 00:23:39,440
But the answer to your first question is I do think healthcare should be profitable.
376
00:23:39,440 --> 00:23:45,960
I think there's a governor on how profitable and some of that is ensuring that it needs
377
00:23:45,960 --> 00:23:50,360
... I think part of the problem right now is, and CMS and some of the other systems
378
00:23:50,360 --> 00:23:54,160
have made an effort towards this, but there is an essential decoupling of quality versus
379
00:23:54,160 --> 00:23:55,640
reimbursement.
380
00:23:55,640 --> 00:24:00,360
And we're moving towards trying to fix that, but in a lot of ways that's almost not fixable
381
00:24:00,360 --> 00:24:01,440
or has not been fixed.
382
00:24:01,440 --> 00:24:05,600
But I think that it is reasonable to make it a profitable system where you're based
383
00:24:05,600 --> 00:24:07,800
on quality and pay for quality.
384
00:24:07,800 --> 00:24:11,920
And the reason I say that is, I know you're saying a decouple innovation, but I think
385
00:24:11,920 --> 00:24:16,720
innovation is driven by that.
386
00:24:16,720 --> 00:24:22,440
People do go into medicine because financially it is satisfying.
387
00:24:22,440 --> 00:24:24,600
You do make good money as a doctor.
388
00:24:24,600 --> 00:24:26,000
It's not a secret.
389
00:24:26,000 --> 00:24:31,920
If you start eliminating the financial benefit, if you're building a system from de novo
390
00:24:31,920 --> 00:24:33,640
and that there's that opportunity, that's different.
391
00:24:33,640 --> 00:24:37,120
But in the current system, if you said, well, doctors are going to start making a 10th of
392
00:24:37,120 --> 00:24:40,600
what they make now, you're going to lose some of the best and brightest from going into
393
00:24:40,600 --> 00:24:43,600
medicine and then quality will drop and et cetera.
394
00:24:43,600 --> 00:24:44,600
There's a fallout from that.
395
00:24:44,600 --> 00:24:49,240
So I think in the confines of the current system, it does need to be profitable, but
396
00:24:49,240 --> 00:24:53,960
I do believe insurance companies have taken this to a different level and the system has
397
00:24:53,960 --> 00:24:58,560
been perverted in order to have oversized returns for United.
398
00:24:58,560 --> 00:25:02,560
If you look at just look at their filing, the amount of money insurance is making is
399
00:25:02,560 --> 00:25:07,360
out of proportion to what we see on the street and what happens in terms of patients being
400
00:25:07,360 --> 00:25:12,920
either not getting a pre-op or being steered towards certain providers or whatever is happening
401
00:25:12,920 --> 00:25:14,560
for the people in the trenches.
402
00:25:14,560 --> 00:25:16,320
Okay, perfect.
403
00:25:16,320 --> 00:25:18,800
Let's talk about tailwinds.
404
00:25:18,800 --> 00:25:23,760
One tailwind I'm banking on as a hybrid home care model for acute care.
405
00:25:23,760 --> 00:25:25,440
Take me back 10 years.
406
00:25:25,440 --> 00:25:29,440
What are some tailwinds you were identifying then that you were right about and what are
407
00:25:29,440 --> 00:25:33,360
some you were wrong about?
408
00:25:33,360 --> 00:25:39,540
So I sort of built at Builders our healthcare thesis around sort of four pillars of which
409
00:25:39,540 --> 00:25:41,360
I think they've all sort of come true.
410
00:25:41,360 --> 00:25:48,880
So the first and the paramount was the concept of moving care from hospital, surgery center,
411
00:25:48,880 --> 00:25:54,480
tertiary care center to the home as much as possible, cheaper, faster, better, more convenient
412
00:25:54,480 --> 00:25:57,120
and using technology in order to do that.
413
00:25:57,120 --> 00:26:01,360
The first iteration or generation of that tech was sort of remote monitoring, IOT, host
414
00:26:01,360 --> 00:26:07,040
of techniques such as that companies like Lavongo and even Fitbits and that kind of
415
00:26:07,040 --> 00:26:08,200
thing have used.
416
00:26:08,200 --> 00:26:14,600
So a concept of moving, it's not necessary to treat a copper strep in a tertiary care
417
00:26:14,600 --> 00:26:16,480
hospital at three grand a visit.
418
00:26:16,480 --> 00:26:20,040
You can do that at home, telemedicine for 15 bucks.
419
00:26:20,040 --> 00:26:26,840
So that is a generic concept of moving care away from the sort of very expensive to cheaper
420
00:26:26,840 --> 00:26:27,840
care centers.
421
00:26:27,840 --> 00:26:31,760
That was a big thesis of which we made some investments around that happening into a company
422
00:26:31,760 --> 00:26:36,460
called Carbon Health and a couple of others.
423
00:26:36,460 --> 00:26:42,840
Second was a true understanding that I think the omics space is going to revolutionize
424
00:26:42,840 --> 00:26:47,760
a lot of what we do whether it's genomics, protanomics, metabolomics, radioma, all of
425
00:26:47,760 --> 00:26:49,640
these omic kind of things.
426
00:26:49,640 --> 00:26:55,200
Basically driven towards a better understanding of each individual rather than at a population
427
00:26:55,200 --> 00:26:56,200
level.
428
00:26:56,200 --> 00:27:00,240
And so I can tell you personally, we see this all the time, people that come into the emergency
429
00:27:00,240 --> 00:27:06,000
room, they have abdominal pain, trigger a CT, which is a thousand dollar test.
430
00:27:06,000 --> 00:27:12,000
They had some bad chicken and they go home because it's a normal CT.
431
00:27:12,000 --> 00:27:18,280
I think we had a test at home that we knew that you had a, you know, whatever it may
432
00:27:18,280 --> 00:27:22,840
be, a tryptophan allergy and you probably shouldn't drink this kind of red wine.
433
00:27:22,840 --> 00:27:25,560
And it's because you had that red wine with your chicken and that's why you have belly
434
00:27:25,560 --> 00:27:26,560
pain.
435
00:27:26,560 --> 00:27:30,140
And we just saved the system a thousand dollars, an ER visit and a CT scan.
436
00:27:30,140 --> 00:27:33,720
So that personalized medicine component of it, I think is coming.
437
00:27:33,720 --> 00:27:38,560
And we're seeing that with companies like Everly Well and a lot of the home testing,
438
00:27:38,560 --> 00:27:42,760
you know, home testing has become much more robust and a lot of companies doing so just,
439
00:27:42,760 --> 00:27:45,280
you know, either whether it's blood, urine.
440
00:27:45,280 --> 00:27:51,520
I was on the board of a company that has a breast cancer detection algorithm out of tears.
441
00:27:51,520 --> 00:27:56,980
So lots of that kind of stuff, saliva, tears, sweat, blood, urine, stool, that having these
442
00:27:56,980 --> 00:28:01,880
tests that will give us a lot more information about an individual that can give us more
443
00:28:01,880 --> 00:28:04,960
preventative healthcare.
444
00:28:04,960 --> 00:28:09,440
Number three was some novel techniques around the finance of healthcare.
445
00:28:09,440 --> 00:28:11,120
So we were an early investor in Oscar.
446
00:28:11,120 --> 00:28:14,800
This is a healthcare insurance company in New York that took advantage of a lot of the
447
00:28:14,800 --> 00:28:15,800
Obamacare.
448
00:28:15,800 --> 00:28:17,480
They were doing some very interesting things with tech.
449
00:28:17,480 --> 00:28:21,040
You know, they were able to, for example, they were one of the first ones who would
450
00:28:21,040 --> 00:28:22,920
give you a fitness tracker.
451
00:28:22,920 --> 00:28:26,840
And if you were using the fitness tracker and walking a certain amount every day, you
452
00:28:26,840 --> 00:28:29,120
would get a reduction on your rates.
453
00:28:29,120 --> 00:28:35,840
They understood, you know, they would look at clusters of claims and they, you know,
454
00:28:35,840 --> 00:28:39,920
I remember a very good example where they had a cluster of asthmatic kids in one area
455
00:28:39,920 --> 00:28:44,280
in New York and they realized what was happening was that there was an infestation of bed bugs
456
00:28:44,280 --> 00:28:47,880
and these bed bugs were eliciting asthmatic reactions in these kids.
457
00:28:47,880 --> 00:28:52,520
So the insurance company paid for exterminators to go exterminate these bed bugs because the
458
00:28:52,520 --> 00:28:57,280
Senate exterminated it out for 59 bucks was cheaper than three hospital visits for the
459
00:28:57,280 --> 00:28:58,280
asthmatic kid.
460
00:28:58,280 --> 00:29:02,560
So, you know, all the understandings of sort of payment mechanisms, both whether it's a
461
00:29:02,560 --> 00:29:07,640
pay-by-their, but whether it's third-party administrators, whether it's ACOs or whatever
462
00:29:07,640 --> 00:29:12,280
it may be, the novel mechanisms of payment for healthcare that can make the system more
463
00:29:12,280 --> 00:29:18,440
efficient and not necessarily do sort of just the conventional insurance model.
464
00:29:18,440 --> 00:29:22,200
And then the last is just AI as a generic catch-all for sort of things.
465
00:29:22,200 --> 00:29:27,200
And, you know, generative AI and diagnostic AI, I hesitate to use that term because every
466
00:29:27,200 --> 00:29:32,320
company we look at now in 2022 has some AI component and it doesn't really mean anything.
467
00:29:32,320 --> 00:29:39,000
But I think there is a rule, especially as a radiologist, we see a ton of AI and my clinical
468
00:29:39,000 --> 00:29:43,200
trial company that we had worked with that did almost all the FDA approvals for all the
469
00:29:43,200 --> 00:29:45,200
AI algorithms and radiology.
470
00:29:45,200 --> 00:29:49,480
So we had a lot of exposure and a lot of work in that space.
471
00:29:49,480 --> 00:29:53,520
But I think that's something that is going to keep on growing.
472
00:29:53,520 --> 00:29:59,120
Okay, I think I have a trillion questions.
473
00:29:59,120 --> 00:30:05,840
The one thing I'll ask first, I ask you the next question, the fitness tracker for reduction
474
00:30:05,840 --> 00:30:07,920
on rates, did that work?
475
00:30:07,920 --> 00:30:08,920
No.
476
00:30:08,920 --> 00:30:11,040
So I think there was two problems.
477
00:30:11,040 --> 00:30:15,800
One is they were using Misfit, which was an old school tracker, which, you know, there's
478
00:30:15,800 --> 00:30:17,440
a limited amount of information.
479
00:30:17,440 --> 00:30:21,720
And we've now invested in a company that is actually the reiteration of Jawbone.
480
00:30:21,720 --> 00:30:25,360
I don't know if you remember that Jawbone had a headset and a boombox.
481
00:30:25,360 --> 00:30:29,160
Well, they've like come back and they actually have a fitness tracker that they went and
482
00:30:29,160 --> 00:30:33,420
bought a bunch of technology for a bunch of sensors, green light sensors from Phillips.
483
00:30:33,420 --> 00:30:38,680
But they're building an ecosystem around a full fitness tracker for humans.
484
00:30:38,680 --> 00:30:42,420
And so you think about it sort of like in your car where you get a red light for when
485
00:30:42,420 --> 00:30:44,160
something's going wrong with the engine.
486
00:30:44,160 --> 00:30:49,160
It's a tracker for it's tracking everything 24 seven in real time, but then informing
487
00:30:49,160 --> 00:30:50,580
you when there's when there's an issue.
488
00:30:50,580 --> 00:30:53,800
So I think tracker technology has progressed a significant amount.
489
00:30:53,800 --> 00:30:54,800
That was number one.
490
00:30:54,800 --> 00:30:57,680
And number two, just adoption by people.
491
00:30:57,680 --> 00:31:02,080
You know, at the end of the day, the problem with that technology was people weren't walking.
492
00:31:02,080 --> 00:31:06,480
Like it wasn't enough of an incentive for them to say, if I get three dollars off my
493
00:31:06,480 --> 00:31:10,160
insurance premium, but I have to walk seven miles a day, I'm not going to do it.
494
00:31:10,160 --> 00:31:11,700
We have more data now.
495
00:31:11,700 --> 00:31:16,960
What is beneficial both from a human hack perspective, from both a diet, from sleep,
496
00:31:16,960 --> 00:31:18,480
from all of these things.
497
00:31:18,480 --> 00:31:20,760
Again, we're talking about personalized medicine, right?
498
00:31:20,760 --> 00:31:23,920
Ketosis, prognomics, intermittent fasting, walking, all of these things.
499
00:31:23,920 --> 00:31:28,280
We just have a better understanding so we can be more meaningful now about what we're
500
00:31:28,280 --> 00:31:32,840
what an insurance company would recommend if you're trying to get a true reduction in
501
00:31:32,840 --> 00:31:33,840
rates.
502
00:31:33,840 --> 00:31:35,960
OK, perfect.
503
00:31:35,960 --> 00:31:39,200
Let's talk about how we make decisions.
504
00:31:39,200 --> 00:31:42,640
And the basis of this is health care is a need.
505
00:31:42,640 --> 00:31:43,980
It's not a want.
506
00:31:43,980 --> 00:31:46,400
We pay more for wants than our needs.
507
00:31:46,400 --> 00:31:51,680
If we look at Robert Cialdini's principles of marketing, and I'm a big fan of his reciprocity,
508
00:31:51,680 --> 00:31:57,680
commitment, consistency, social proof, liking and scarcity, needing something is not a principle.
509
00:31:57,680 --> 00:32:02,760
How do we gamify health care so prevention is a want, not a need?
510
00:32:02,760 --> 00:32:05,680
Yeah, I mean, it's interesting.
511
00:32:05,680 --> 00:32:11,920
I would say, if I put my investor hat on, I don't think I'm not prepared right now to
512
00:32:11,920 --> 00:32:16,720
make bets in gamifying health care just because human behavior, the way the system is set
513
00:32:16,720 --> 00:32:19,120
up probably doesn't lend itself to being successful.
514
00:32:19,120 --> 00:32:22,920
I think the things that we've the companies we've seen have tried to gamify things have
515
00:32:22,920 --> 00:32:25,760
not traditionally been overly successful.
516
00:32:25,760 --> 00:32:30,400
Not that it can't be done in specific things for children, for you know, it works.
517
00:32:30,400 --> 00:32:35,240
But I think as an overall health care system, I think that's difficult to do.
518
00:32:35,240 --> 00:32:41,480
So I think, you know, for me personally, some of that the motivation to do that again is
519
00:32:41,480 --> 00:32:44,840
I strongly believe, unfortunately, or fortunately, is driven by money.
520
00:32:44,840 --> 00:32:49,400
You know, if your insurance rates are lower, we've seen and shown that people are motivated
521
00:32:49,400 --> 00:32:50,480
to do things.
522
00:32:50,480 --> 00:32:53,920
And then there's an upper and a lower band of what is considered reasonable, right?
523
00:32:53,920 --> 00:32:58,600
Like, you know, if we said to you, we'll reduce your insurance by, like I said, $5, but you
524
00:32:58,600 --> 00:33:00,720
have to walk 10 miles a day, you're not going to do it.
525
00:33:00,720 --> 00:33:05,000
But if we reduce your insurance by $50, and you have to walk three miles, maybe you'll
526
00:33:05,000 --> 00:33:06,000
do it.
527
00:33:06,000 --> 00:33:10,120
So there's some upper and lower band of human dynamics that you just need to understand.
528
00:33:10,120 --> 00:33:14,120
And we're looking and working with insurance providers who are trying to figure that out.
529
00:33:14,120 --> 00:33:18,000
You know, in a they're trying to figure out in a smaller cohort, we're working with a
530
00:33:18,000 --> 00:33:21,160
company that works only with small businesses, and they have a lot of healthy population.
531
00:33:21,160 --> 00:33:24,280
And so they're able to do that because they are there.
532
00:33:24,280 --> 00:33:27,280
There's not a lot of variation between their sickest and their healthiest person.
533
00:33:27,280 --> 00:33:29,920
So they have an internal control that they can look at.
534
00:33:29,920 --> 00:33:36,680
So I think it's it's understanding human behavior and human dynamic, and then trying to layer
535
00:33:36,680 --> 00:33:44,160
on realistic things that will allow those things to be to be valuable.
536
00:33:44,160 --> 00:33:47,160
And I remember, you know, there was a time when I was looking at, you know, trying to
537
00:33:47,160 --> 00:33:48,160
health hack myself.
538
00:33:48,160 --> 00:33:51,600
And I was watching these movies, Game Changers and Fat, Sick and Nearly Dead.
539
00:33:51,600 --> 00:33:54,520
And this guy was like juicing himself across the country.
540
00:33:54,520 --> 00:33:58,520
And I remember I live in Texas, but I remember this very vividly sat down with these these
541
00:33:58,520 --> 00:34:01,080
people in a in some barbecue place in Texas.
542
00:34:01,080 --> 00:34:03,760
And I said, you know, I'm juicing my way across the country.
543
00:34:03,760 --> 00:34:07,000
And the guy said, I'd rather die than not eat barbecue.
544
00:34:07,000 --> 00:34:10,240
And I think that that sentiment is probably there are people who are like, it doesn't
545
00:34:10,240 --> 00:34:11,240
matter.
546
00:34:11,240 --> 00:34:16,760
I'd rather smoke, drink, eat this, that, whatever, and just die happy than, you know, eat lettuce
547
00:34:16,760 --> 00:34:19,280
every day for 30 years and live an extra 20.
548
00:34:19,280 --> 00:34:22,600
I mean, there's just there's a human dynamic component that you have to understand.
549
00:34:22,600 --> 00:34:25,760
And it's very population driven in the population you're serving.
550
00:34:25,760 --> 00:34:29,920
And so it's a local and regional thing that you have to look at.
551
00:34:29,920 --> 00:34:33,720
And I think the companies that we're looking at are successful, have different models for
552
00:34:33,720 --> 00:34:34,720
different regions.
553
00:34:34,720 --> 00:34:35,720
Perfect.
554
00:34:35,720 --> 00:34:36,720
I'll say something a little bit inappropriate.
555
00:34:36,720 --> 00:34:37,720
I don't know if I should.
556
00:34:37,720 --> 00:34:38,720
I looked into juicing.
557
00:34:38,720 --> 00:34:45,720
And the reason I didn't do it is because there was a lot of mention of enemas.
558
00:34:45,720 --> 00:34:46,720
Yeah.
559
00:34:46,720 --> 00:34:49,720
Let's talk about each other.
560
00:34:49,720 --> 00:34:50,720
Yeah, exactly.
561
00:34:50,720 --> 00:34:54,960
But not for me, just to clarify.
562
00:34:54,960 --> 00:35:00,420
Let's talk about how to best incentivize people for healthy behavior.
563
00:35:00,420 --> 00:35:03,680
And I'll just give you two options to make it simple.
564
00:35:03,680 --> 00:35:08,360
Is it better to tug at loss prevention, which is essentially reducing rates or asking people
565
00:35:08,360 --> 00:35:13,320
for money and giving them back some if they meet the targets?
566
00:35:13,320 --> 00:35:19,960
Or is it better to tug at positive reinforcement or give them money on top of whatever the
567
00:35:19,960 --> 00:35:20,960
rates are?
568
00:35:20,960 --> 00:35:27,960
And it's more of a way of how you phrase or deliver this reward that is essentially the
569
00:35:27,960 --> 00:35:29,000
game here.
570
00:35:29,000 --> 00:35:31,480
Which one do you think is better?
571
00:35:31,480 --> 00:35:37,280
I would say all of the education and reading that I've done would illustrate that positive
572
00:35:37,280 --> 00:35:38,880
reinforcement is better than negative.
573
00:35:38,880 --> 00:35:42,000
Carrots are better than sticks.
574
00:35:42,000 --> 00:35:46,140
I would say that my real world experience of the same thing and me personally has been
575
00:35:46,140 --> 00:35:51,600
a reduction in rate or whatever is more motivating than the other side.
576
00:35:51,600 --> 00:35:54,120
So I don't know the answer to that question.
577
00:35:54,120 --> 00:35:56,720
We've looked at companies that have done both.
578
00:35:56,720 --> 00:36:02,240
So we've made investments in the secondary healthcare companies that run incentive programs.
579
00:36:02,240 --> 00:36:04,600
If you join the gym, you get a discount.
580
00:36:04,600 --> 00:36:07,760
If you do something else, you get a free Apple Watch.
581
00:36:07,760 --> 00:36:10,820
So that's the two things you're talking about.
582
00:36:10,820 --> 00:36:13,560
One is a reduction because you do some of the other is you get a free Apple Watch if
583
00:36:13,560 --> 00:36:15,560
you do this.
584
00:36:15,560 --> 00:36:20,060
And I think when they've studied that, it's been very, again, very heterogeneous depending
585
00:36:20,060 --> 00:36:22,560
on the population they're serving.
586
00:36:22,560 --> 00:36:24,880
And it's not one size fits all.
587
00:36:24,880 --> 00:36:28,960
A 75-year-old probably doesn't care about getting an Apple Watch.
588
00:36:28,960 --> 00:36:31,560
A 21-year-old wants an Apple Watch.
589
00:36:31,560 --> 00:36:36,320
The 21-year-old doesn't understand a reduction in rate will give you money that you can compound
590
00:36:36,320 --> 00:36:39,560
interest for the rest of your life and become a millionaire because you are healthy.
591
00:36:39,560 --> 00:36:44,880
The 75-year-old, so it's very different and you have to, it has to be applicable to the
592
00:36:44,880 --> 00:36:47,000
population that you're trying to serve.
593
00:36:47,000 --> 00:36:48,680
And that I think has been part of the problem.
594
00:36:48,680 --> 00:36:52,080
It's a one size fits all and it doesn't fit all.
595
00:36:52,080 --> 00:36:56,520
And so some of these innovative payments, like we have a family of four, we're fairly
596
00:36:56,520 --> 00:36:57,520
healthy.
597
00:36:57,520 --> 00:36:59,080
We use almost no healthcare.
598
00:36:59,080 --> 00:37:04,360
I pay a huge deductible, a huge premium every month, but we don't use healthcare because
599
00:37:04,360 --> 00:37:06,640
we're at a phase in our life where we're healthy.
600
00:37:06,640 --> 00:37:07,640
We'll need that later.
601
00:37:07,640 --> 00:37:11,680
Well, if you gave me an incentive to save some money and do things that would set up
602
00:37:11,680 --> 00:37:14,960
the insurance company and you could amortize that over some period of years, that would
603
00:37:14,960 --> 00:37:16,120
be a novel way of doing it.
604
00:37:16,120 --> 00:37:19,560
So we're looking at sort of those kinds of models where insurance companies are saying,
605
00:37:19,560 --> 00:37:21,200
let's take a small cohort.
606
00:37:21,200 --> 00:37:25,080
We have to analyze you as a cohort and see whether this fits for you.
607
00:37:25,080 --> 00:37:28,280
Traditionally, that's been too much manpower to do that.
608
00:37:28,280 --> 00:37:33,900
But now with algorithms, AI, whatever it may be, you can get that information on a much
609
00:37:33,900 --> 00:37:36,920
more efficient basis and make those decisions.
610
00:37:36,920 --> 00:37:41,860
So I mean, we looked at a company that on your phone, it can read all your vitals.
611
00:37:41,860 --> 00:37:47,040
So just by looking at the screen, it projects a red light, projects it off your skin, gets
612
00:37:47,040 --> 00:37:51,640
heart rate, temperature, O2 saturation, blood pressure, all from that.
613
00:37:51,640 --> 00:37:54,360
They're starting a pilot with an insurance company in Europe.
614
00:37:54,360 --> 00:37:56,520
So if you not even, you don't even have to check in.
615
00:37:56,520 --> 00:38:01,200
If you put the app on your phone, when you do FaceTime or whatever, or unlock your phone,
616
00:38:01,200 --> 00:38:03,200
it records that data and sends it to the insurance company.
617
00:38:03,200 --> 00:38:07,600
So now insurance company has a longitudinal view of your blood pressure, your heart rate,
618
00:38:07,600 --> 00:38:11,040
and now they can do your premiums without you having to do anything.
619
00:38:11,040 --> 00:38:16,280
That kind of novel stuff is I think where the future of this is where you can now, like
620
00:38:16,280 --> 00:38:21,480
you said, cancer and surgery, you can still pay for quality up there.
621
00:38:21,480 --> 00:38:25,400
Because the number of people using that is less out of the general population, but it's
622
00:38:25,400 --> 00:38:28,520
not the general population subsidizing that anymore.
623
00:38:28,520 --> 00:38:33,200
You can actually divert dollars where they need to go and save money where it doesn't
624
00:38:33,200 --> 00:38:37,940
need to go and have a very novel sort of payment and an insurance mechanism as opposed to this
625
00:38:37,940 --> 00:38:39,240
one size fits all.
626
00:38:39,240 --> 00:38:41,560
Yeah, I think that makes sense.
627
00:38:41,560 --> 00:38:48,960
Risk pooling is needed, but distribution of that risk can be triaged and personalized.
628
00:38:48,960 --> 00:38:51,200
What's the end game for you, Amit?
629
00:38:51,200 --> 00:38:57,640
If we define retirement by when you reach a point where every day is complete in itself,
630
00:38:57,640 --> 00:39:02,960
you're looking forward to things, but you're perfectly happy with the day as it was.
631
00:39:02,960 --> 00:39:05,420
Would you consider self-retire right now?
632
00:39:05,420 --> 00:39:10,900
And then the second part of this question is, I'll take you 50 years down the line.
633
00:39:10,900 --> 00:39:17,000
What do the last five years of your life look like in an ideal world?
634
00:39:17,000 --> 00:39:21,400
I think my wife probably has a very different answer to this question than I do.
635
00:39:21,400 --> 00:39:24,000
So for me, I don't think there is retirement.
636
00:39:24,000 --> 00:39:28,620
Part of what I like about investing and what I like is I pick a topic every year and go
637
00:39:28,620 --> 00:39:34,200
deep and try to understand, read, experience, whatever it may be around that topic.
638
00:39:34,200 --> 00:39:35,800
And there's no end of topics.
639
00:39:35,800 --> 00:39:37,920
And I enjoy doing that.
640
00:39:37,920 --> 00:39:39,840
So I'll continue to do that.
641
00:39:39,840 --> 00:39:44,480
And as long as I can be in it, obviously, there's a potential finite life as an investor.
642
00:39:44,480 --> 00:39:47,360
I mean, if your funds aren't returning, then there is no next fund.
643
00:39:47,360 --> 00:39:50,080
And it may be self-fulfilling that it's over for me.
644
00:39:50,080 --> 00:39:57,600
I'll continue to do the intellectual and experiential investigation that I do now on a yearly basis.
645
00:39:57,600 --> 00:40:02,920
But I think there's a physical component to when do you tire out?
646
00:40:02,920 --> 00:40:10,680
I stand in a lab 13 hours a day wearing lead, heavy lead for when I'm doing cases.
647
00:40:10,680 --> 00:40:14,880
At some point, physically, you wear out from being able to do that.
648
00:40:14,880 --> 00:40:15,880
But I'm not at that point.
649
00:40:15,880 --> 00:40:17,480
So I think I enjoy that.
650
00:40:17,480 --> 00:40:21,520
I'm now that I'll keep doing that until physically I'm not capable.
651
00:40:21,520 --> 00:40:24,280
But one thing that I've learned to do is multitask.
652
00:40:24,280 --> 00:40:28,880
And so while I can pursue these intellectual things at my level of my satisfaction, I'll
653
00:40:28,880 --> 00:40:30,980
just keep doing that till I can.
654
00:40:30,980 --> 00:40:35,360
So I don't know what the last five years, that last five is.
655
00:40:35,360 --> 00:40:40,240
I think there's a sentence that, tell me how I'm going to die so I can avoid it.
656
00:40:40,240 --> 00:40:47,600
So when that's coming, I hope I have some personalized medicine, genomic, proteomics
657
00:40:47,600 --> 00:40:53,240
markers that will tell me that you have 447 days left.
658
00:40:53,240 --> 00:40:54,520
Would you want to know?
659
00:40:54,520 --> 00:40:56,280
Yeah, I think I would.
660
00:40:56,280 --> 00:41:00,160
I mean, my personality is I'd rather know than not know.
661
00:41:00,160 --> 00:41:01,900
Both our kids, I'm a radiologist.
662
00:41:01,900 --> 00:41:04,640
We ultrasounded them in the first time.
663
00:41:04,640 --> 00:41:07,800
We knew what sex of kids we were going to have before we had them.
664
00:41:07,800 --> 00:41:08,800
There was no surprises.
665
00:41:08,800 --> 00:41:10,880
We're not doing, there was no gender reveal stuff.
666
00:41:10,880 --> 00:41:15,680
So yeah, I've always been a personality that I'd rather know and deal with what it is and
667
00:41:15,680 --> 00:41:17,880
have the knowledge rather than the surprise.
668
00:41:17,880 --> 00:41:19,760
The surprise doesn't engage me.
669
00:41:19,760 --> 00:41:20,760
Interesting.
670
00:41:20,760 --> 00:41:26,160
What's the perfect birthday for you?
671
00:41:26,160 --> 00:41:31,160
You know, I mean, I like to, you know, this sort of, I like to work.
672
00:41:31,160 --> 00:41:32,480
Like I like to do things.
673
00:41:32,480 --> 00:41:37,000
And so it doesn't necessarily have to be medicine or investing or these other things that I
674
00:41:37,000 --> 00:41:38,840
do, but active things.
675
00:41:38,840 --> 00:41:41,320
So obviously spend time.
676
00:41:41,320 --> 00:41:42,560
Family is obviously very important.
677
00:41:42,560 --> 00:41:49,160
You know, we have young kids, so probably that's the majority of it is that carve out
678
00:41:49,160 --> 00:41:55,040
time specifically to be with family during what is usually a very hectic week.
679
00:41:55,040 --> 00:42:01,720
Do you work on your birthday?
680
00:42:01,720 --> 00:42:04,200
I work if I have to.
681
00:42:04,200 --> 00:42:11,440
If I, if I can maneuver out of it, I would, but if I have to, I would.
682
00:42:11,440 --> 00:42:17,480
Would you classify yourself as an operator, someone excellent at execution or a visionary?
683
00:42:17,480 --> 00:42:23,840
And when you look at a founding team, do you look for both and which one is easier to replace
684
00:42:23,840 --> 00:42:27,600
or find source externally from your network?
685
00:42:27,600 --> 00:42:31,800
It's an interesting question.
686
00:42:31,800 --> 00:42:35,320
It's hard to say you're a vision, in my opinion, to say you're a visionary without being an
687
00:42:35,320 --> 00:42:36,760
egotistical visionary.
688
00:42:36,760 --> 00:42:39,640
So I'm going to, I'm going to dance away from that.
689
00:42:39,640 --> 00:42:45,240
But I think, yeah, my, I think my skillset has been more around strategy and vision than
690
00:42:45,240 --> 00:42:46,240
operation.
691
00:42:46,240 --> 00:42:51,120
You know, when we accepted this company, my company, I mean, I got on the ground and plugged
692
00:42:51,120 --> 00:42:57,560
in computers and wrote SOPs and did whatever it took as an operator, more as a skillset,
693
00:42:57,560 --> 00:43:02,480
learning how to do it so that, you know, when someone failed at it, I was the backup, I
694
00:43:02,480 --> 00:43:03,600
could do it.
695
00:43:03,600 --> 00:43:08,040
I wouldn't say I enjoyed the operational component as much as the strategy, vision, guidance
696
00:43:08,040 --> 00:43:09,040
part of it.
697
00:43:09,040 --> 00:43:12,240
And so I think also, you know, as you look at things that you do in your life and you
698
00:43:12,240 --> 00:43:16,080
converge into things that are more your personality, you know, as it takes time to figure that
699
00:43:16,080 --> 00:43:20,360
out, you know, that's why I prefer to be on the board of a company and help with direction
700
00:43:20,360 --> 00:43:26,200
and strategy using the experience from being an operator to help them rather than, than
701
00:43:26,200 --> 00:43:27,200
being the operator.
702
00:43:27,200 --> 00:43:29,720
Having said that, we've been toying with being an operator again.
703
00:43:29,720 --> 00:43:32,920
Your friend of mine has come to me and said, like, let's start another company.
704
00:43:32,920 --> 00:43:39,680
And so maybe that does come again, but it has to be the right idea and the right execution.
705
00:43:39,680 --> 00:43:45,400
But I prefer the, you know, he's an, he's an incredible operator and has operated at
706
00:43:45,400 --> 00:43:47,160
a very high level.
707
00:43:47,160 --> 00:43:50,440
So we compliment each other really well and that I'm more strategy vision.
708
00:43:50,440 --> 00:43:53,520
He's very operate, he's less strategy vision.
709
00:43:53,520 --> 00:43:56,280
And you know, so that compliment works well.
710
00:43:56,280 --> 00:44:01,240
And do you look for both in a founding team and which one is easier to source from your
711
00:44:01,240 --> 00:44:02,240
network?
712
00:44:02,240 --> 00:44:03,240
I mean, absolutely.
713
00:44:03,240 --> 00:44:06,200
I look for it in a founding team.
714
00:44:06,200 --> 00:44:08,640
I mean, it's always in the back of your mind.
715
00:44:08,640 --> 00:44:12,320
The issue is more at the stage of when you're making an investment.
716
00:44:12,320 --> 00:44:17,440
So if it's a series CD, whatever, I mean, they figured it out, right?
717
00:44:17,440 --> 00:44:20,040
I mean, you're not getting to a hundred million in revenue.
718
00:44:20,040 --> 00:44:26,360
If the CEO is a tech guy, was no tech person who has no operational experience and can't
719
00:44:26,360 --> 00:44:27,360
motivate people.
720
00:44:27,360 --> 00:44:28,800
Like it's just not going to happen.
721
00:44:28,800 --> 00:44:29,800
Right.
722
00:44:29,800 --> 00:44:35,080
Or it's very rare that that happens at the stage where we invest, which is seed and a,
723
00:44:35,080 --> 00:44:39,920
all of that is very important, but hasn't necessarily always manifested.
724
00:44:39,920 --> 00:44:44,640
So we see lots of companies where the CEO is great for the seed or for the early a,
725
00:44:44,640 --> 00:44:49,880
but once you get to a B or a C, they really need to step aside and bring in adult supervision,
726
00:44:49,880 --> 00:44:52,000
so to speak, because it's not there.
727
00:44:52,000 --> 00:44:56,320
They're a great founding CEO and they're the ones, you know, two guys in a garage, you
728
00:44:56,320 --> 00:45:01,280
know, all of that sort of stuff, but they're not the ones that sit with an investment bank
729
00:45:01,280 --> 00:45:03,760
to negotiate, you know, book running an IPO.
730
00:45:03,760 --> 00:45:05,600
I mean, that's not who they are, right?
731
00:45:05,600 --> 00:45:08,840
They don't, the attention to detail, the experience, whatever it may be.
732
00:45:08,840 --> 00:45:12,400
And so that, I think it's very much dependent on what stage you're investing at to figure
733
00:45:12,400 --> 00:45:14,560
out who the right founders are.
734
00:45:14,560 --> 00:45:15,560
Okay.
735
00:45:15,560 --> 00:45:22,440
You know, something I'm doing right now is looking at companies that have made it and
736
00:45:22,440 --> 00:45:25,240
going back to see if I would have invested in them.
737
00:45:25,240 --> 00:45:29,560
And oftentimes the answer I'm getting is no.
738
00:45:29,560 --> 00:45:33,880
The companies I'm talking about, I'll just say some names as Romans and Four Hymns, you
739
00:45:33,880 --> 00:45:39,640
know, they've done really well and they're pivoting to more being almost at home hybrid
740
00:45:39,640 --> 00:45:43,760
health system, which is great, but that's not what they were when they started.
741
00:45:43,760 --> 00:45:45,200
Do you do this exercise?
742
00:45:45,200 --> 00:45:49,400
Do you go back and look at companies you did not invest in and maybe you didn't come across
743
00:45:49,400 --> 00:45:52,040
or you did and you passed on them?
744
00:45:52,040 --> 00:45:56,720
And then do you change your investment thesis to any extent and say if you get one of these
745
00:45:56,720 --> 00:46:01,320
or say if you get 10 of these companies?
746
00:46:01,320 --> 00:46:05,240
I would tell you, I don't do the exercise, but my partners definitely do the exercise
747
00:46:05,240 --> 00:46:07,240
for me because they send me the deals.
748
00:46:07,240 --> 00:46:08,500
You said no on this.
749
00:46:08,500 --> 00:46:10,040
Look at this billion dollar exit.
750
00:46:10,040 --> 00:46:11,680
So no, I'm kidding.
751
00:46:11,680 --> 00:46:12,680
They don't.
752
00:46:12,680 --> 00:46:14,120
Thankfully we have a great partnership.
753
00:46:14,120 --> 00:46:15,120
We don't do that.
754
00:46:15,120 --> 00:46:23,960
But I would say I do, I look at that from a, from a just an experiential intellectual
755
00:46:23,960 --> 00:46:24,960
perspective.
756
00:46:24,960 --> 00:46:27,920
I don't beat myself up about not making the investment.
757
00:46:27,920 --> 00:46:31,200
I mean, some of these ones that you're talking about, we had the opportunity to invest.
758
00:46:31,200 --> 00:46:35,160
I think if you stay fundamental to a thesis, some things just don't fit.
759
00:46:35,160 --> 00:46:37,880
And those, the ones that you hear about are the outliers.
760
00:46:37,880 --> 00:46:42,320
One thing I've learned when I got into investing, I mean, we look at 70, 80, a hundred deals
761
00:46:42,320 --> 00:46:43,320
a week, right?
762
00:46:43,320 --> 00:46:46,080
But you can't invest in all of them.
763
00:46:46,080 --> 00:46:50,720
And the ones that make the headlines are the ones that break away like that.
764
00:46:50,720 --> 00:46:56,040
But categorically, if it doesn't fit your thesis, then you'll make a mistake 99 times
765
00:46:56,040 --> 00:46:57,960
and have success once.
766
00:46:57,960 --> 00:47:03,040
And I think that's okay in venture if you've right sized your venture investments probably,
767
00:47:03,040 --> 00:47:07,160
you know, that one has a hundred billion exits, so to speak.
768
00:47:07,160 --> 00:47:11,760
It's fine that the 99 went to zero in venture math, but you better be pretty sure that you
769
00:47:11,760 --> 00:47:16,120
can do that on a repeated basis or there is no fun two or fun three or fun four.
770
00:47:16,120 --> 00:47:22,360
So I don't beat myself about the misses, but I do, I do look at them and I try to understand,
771
00:47:22,360 --> 00:47:26,800
you know, did I actually miss something or is this off thesis or this is a one off?
772
00:47:26,800 --> 00:47:30,400
Yeah, I'm really happy you said that.
773
00:47:30,400 --> 00:47:31,400
And I agree with it.
774
00:47:31,400 --> 00:47:34,640
You should not define your thesis chasing after Google.
775
00:47:34,640 --> 00:47:36,560
It was the 18th search engine.
776
00:47:36,560 --> 00:47:40,860
If you decided this wasn't for you after the 16th one, you would have missed out.
777
00:47:40,860 --> 00:47:47,040
So it's something you just have to have an infinite amount of money to pull off, I feel.
778
00:47:47,040 --> 00:47:48,040
Yeah.
779
00:47:48,040 --> 00:47:49,400
I mean, a lot of these businesses, you know, it's interesting.
780
00:47:49,400 --> 00:47:54,880
We've made an investment in a company called Stampede, which is a novel movie studio.
781
00:47:54,880 --> 00:48:02,800
This guy named Greg Silverman, who was the producer manager at Warner Brothers for 20
782
00:48:02,800 --> 00:48:06,160
years, super successful, highest grossing producer of all time.
783
00:48:06,160 --> 00:48:09,920
He did Harry Potter series, Batman, Hangover.
784
00:48:09,920 --> 00:48:12,040
This guy, I mean, this is the guy.
785
00:48:12,040 --> 00:48:19,040
We ran an exercise at our annual meeting last month where he had a grid of seven by seven
786
00:48:19,040 --> 00:48:23,000
movies, which were script titles that were pitched to him.
787
00:48:23,000 --> 00:48:29,760
And we were supposed to pick based on, you know, it was a British kid who is a wizard
788
00:48:29,760 --> 00:48:36,600
who lives below a stairwell and has plays at this school that's, you know, whatever.
789
00:48:36,600 --> 00:48:38,720
And everyone's like, absolutely would never do that.
790
00:48:38,720 --> 00:48:39,720
Right.
791
00:48:39,720 --> 00:48:40,720
It was Harry Potter.
792
00:48:40,720 --> 00:48:44,280
And so it was interesting when you go through what they, you know, his trade craft and his
793
00:48:44,280 --> 00:48:45,840
discipline of picking these movies.
794
00:48:45,840 --> 00:48:49,240
I mean, he can obviously pick winners.
795
00:48:49,240 --> 00:48:52,640
The skill set to pick, I mean, he even said it in our meeting.
796
00:48:52,640 --> 00:48:54,040
We get lucky sometimes, right?
797
00:48:54,040 --> 00:48:56,400
Like there are outliers to the Harry Potter.
798
00:48:56,400 --> 00:49:01,360
He picked he was everyone had rejected that every studio had rejected the books before,
799
00:49:01,360 --> 00:49:05,580
you know, and now look at the one of the great biggest grossing franchises of all time.
800
00:49:05,580 --> 00:49:10,800
So I think you could learn from it, but I don't like you said, I don't we don't I try
801
00:49:10,800 --> 00:49:13,800
not to define by what I consider mistakes.
802
00:49:13,800 --> 00:49:19,040
Do you think you learn more from your successes than your failures?
803
00:49:19,040 --> 00:49:20,320
And I will give my answer.
804
00:49:20,320 --> 00:49:21,320
Yes.
805
00:49:21,320 --> 00:49:23,840
I have learned more from my successes.
806
00:49:23,840 --> 00:49:25,960
And I know this is not the popular answer.
807
00:49:25,960 --> 00:49:32,000
I have learned humility and introspection and reflection from my failures.
808
00:49:32,000 --> 00:49:36,600
But in terms of decision making, I feel like I've learned more from successes.
809
00:49:36,600 --> 00:49:38,800
Yeah, I would agree with that.
810
00:49:38,800 --> 00:49:40,120
I mean, I think I've learned more from the success.
811
00:49:40,120 --> 00:49:45,000
But I think what I've learned from failures is how to be more successful, not necessarily
812
00:49:45,000 --> 00:49:47,880
learn a task or a skill or an idea.
813
00:49:47,880 --> 00:49:54,760
It was, you know, we had we invested in a company where the founder had, you know, we
814
00:49:54,760 --> 00:49:59,960
should have done better due diligence on the founder and his background, etc, etc.
815
00:49:59,960 --> 00:50:03,040
So now, you know, we run a background check on everybody before we make it like those
816
00:50:03,040 --> 00:50:04,040
kinds of things.
817
00:50:04,040 --> 00:50:07,760
They're operational infrastructure things that I think I've learned over the years.
818
00:50:07,760 --> 00:50:12,480
Investor, you know, I've never done a reverse merger IPO with an Israeli shell company.
819
00:50:12,480 --> 00:50:16,560
Well, now we've sort of done it and we understand how to like those kinds of things from those
820
00:50:16,560 --> 00:50:20,760
kinds of failures where we ended up in a situation that we had to navigate out of.
821
00:50:20,760 --> 00:50:25,080
We've learned something that now for other companies that we have, we have a better toolbox
822
00:50:25,080 --> 00:50:27,960
of saying, hey, this is one of the possibilities now.
823
00:50:27,960 --> 00:50:31,640
So I don't for me, it's not been so cut and dry of the conventional, you know, is your
824
00:50:31,640 --> 00:50:34,440
success versus failure learning.
825
00:50:34,440 --> 00:50:37,840
And you know, you teach this to your kids or they tell you to teach it to your kids
826
00:50:37,840 --> 00:50:41,680
that your kids fail so that they can understand success kind of thing.
827
00:50:41,680 --> 00:50:45,220
It's so different, I think, in investing and understanding how this kind of stuff works,
828
00:50:45,220 --> 00:50:51,560
because there's a mechanistic component to just investing, like how to read a term sheet
829
00:50:51,560 --> 00:50:56,760
and how to do a deal and IPO and this and caps and all of these things that come into
830
00:50:56,760 --> 00:51:01,040
liquidity preference, how it all works, that plays such an important role in success or
831
00:51:01,040 --> 00:51:02,040
failure.
832
00:51:02,040 --> 00:51:03,560
You can have something that's very successful.
833
00:51:03,560 --> 00:51:07,440
We're looking at a company right now that they're recapping the company.
834
00:51:07,440 --> 00:51:09,920
We looked a few years ago, it was too rich for our blood.
835
00:51:09,920 --> 00:51:14,880
Now they're recapping the company where the founders have ended up with 1% of the company
836
00:51:14,880 --> 00:51:19,120
after two rounds and that everyone's realized that there is no company unless we recap the
837
00:51:19,120 --> 00:51:21,280
company and give the founders back 30% equity.
838
00:51:21,280 --> 00:51:24,120
You know, that kind of thing is just an experiential thing.
839
00:51:24,120 --> 00:51:26,040
It's got nothing to do with no one fail.
840
00:51:26,040 --> 00:51:29,560
It's just the fundraising went in a way that there were so many people involved that the
841
00:51:29,560 --> 00:51:33,440
cap table got completely squeezed down that these guys sold all their equity out and now
842
00:51:33,440 --> 00:51:34,760
there's no motivation to grow a company.
843
00:51:34,760 --> 00:51:36,160
But the company is good.
844
00:51:36,160 --> 00:51:40,080
So there's investors who are interested in recapping the company.
845
00:51:40,080 --> 00:51:47,000
Okay, let's talk about hiring employees, co-founders and finding a partner.
846
00:51:47,000 --> 00:51:53,040
The lens I want you to answer this question through is Danny Kahneman's decision-making
847
00:51:53,040 --> 00:51:56,040
framework.
848
00:51:56,040 --> 00:52:01,320
I used to hire based on intuition and that was the wrong thing for me.
849
00:52:01,320 --> 00:52:08,580
I've made some terrible mistakes because how do you approach hiring employees and looking
850
00:52:08,580 --> 00:52:14,680
for a co-founder, do you have a structured approach and how do you factor in intuition?
851
00:52:14,680 --> 00:52:20,080
Yeah, I mean, I think co-founder is a very different whole thing, right?
852
00:52:20,080 --> 00:52:24,120
I mean, co-founder is there's a personal component, a professional component, an intellectual
853
00:52:24,120 --> 00:52:25,680
component and a financial component.
854
00:52:25,680 --> 00:52:31,240
I mean, it's very different and that for me and all of the things that I've done where
855
00:52:31,240 --> 00:52:35,960
I've had a co-founder or a partner in a business has been we were friends first and then we
856
00:52:35,960 --> 00:52:38,120
moved into a business relationship.
857
00:52:38,120 --> 00:52:44,520
And we've but very upfront built a business relationship with tax and blocks and tackles
858
00:52:44,520 --> 00:52:49,520
in the documents that shotgun clauses, whatever it was that we understand upfront that if
859
00:52:49,520 --> 00:52:53,200
we get into a fight, which everyone tells you don't do business with your friends, which
860
00:52:53,200 --> 00:52:57,900
I have done business with all my friends is we just build a way that there's a structure
861
00:52:57,900 --> 00:53:00,480
that no one gets into a fight and everyone understands how it's going to be.
862
00:53:00,480 --> 00:53:03,660
So I think as a co-founder, it's a very different exercise.
863
00:53:03,660 --> 00:53:09,880
On the employee side, both my company, our fund, all of these other things, we've tried
864
00:53:09,880 --> 00:53:13,800
360 evaluations and neograms.
865
00:53:13,800 --> 00:53:19,240
There's a host of tools that you fill in these questions, all of this stuff.
866
00:53:19,240 --> 00:53:24,640
I personally have never had that much success with these orchestrated tools.
867
00:53:24,640 --> 00:53:29,300
I think they give you, if you have a limited time of assessment with somebody, they do
868
00:53:29,300 --> 00:53:34,840
give you insight that's very valuable in terms of are they a high performer?
869
00:53:34,840 --> 00:53:36,760
Are they obsessive compulsive?
870
00:53:36,760 --> 00:53:40,480
Whatever these factors that you're looking for.
871
00:53:40,480 --> 00:53:45,160
But I think if you spend enough time with somebody that all of those things as an employer,
872
00:53:45,160 --> 00:53:47,780
as a partner, we're able to garner.
873
00:53:47,780 --> 00:53:49,640
And so that's what we try to focus on.
874
00:53:49,640 --> 00:53:53,840
We try to spend a good amount of time with someone upfront and then to a certain extent
875
00:53:53,840 --> 00:53:56,360
hope for the best.
876
00:53:56,360 --> 00:54:00,720
I've been proven wrong on lots of the 360 evaluations that we've done where the thing
877
00:54:00,720 --> 00:54:04,920
says this person is awesome and they turn out to be awful and vice versa.
878
00:54:04,920 --> 00:54:08,320
We've had people who we thought there's no way this person could succeed and then they're
879
00:54:08,320 --> 00:54:11,680
the most successful person on whatever entity it was.
880
00:54:11,680 --> 00:54:12,680
Okay.
881
00:54:12,680 --> 00:54:13,960
Do you have time for one more question?
882
00:54:13,960 --> 00:54:14,960
If not, we can...
883
00:54:14,960 --> 00:54:15,960
I do.
884
00:54:15,960 --> 00:54:16,960
Yeah.
885
00:54:16,960 --> 00:54:17,960
Let's talk about...
886
00:54:17,960 --> 00:54:23,920
And I had questions for each one of the four pillars and I think maybe in the next round
887
00:54:23,920 --> 00:54:26,040
we'll get to it.
888
00:54:26,040 --> 00:54:28,520
I'm already marking down the next round by the way.
889
00:54:28,520 --> 00:54:33,680
Let's talk about AI and explainability.
890
00:54:33,680 --> 00:54:36,240
I talked to this about Amit from Tao Ventures.
891
00:54:36,240 --> 00:54:37,240
I don't know if you know him.
892
00:54:37,240 --> 00:54:38,240
I do.
893
00:54:38,240 --> 00:54:40,160
We're invested in a company together actually.
894
00:54:40,160 --> 00:54:41,160
Okay.
895
00:54:41,160 --> 00:54:42,160
Yeah.
896
00:54:42,160 --> 00:54:44,560
And he gave an amazing answer.
897
00:54:44,560 --> 00:54:46,360
So the pressure is on Amit.
898
00:54:46,360 --> 00:54:47,360
All right.
899
00:54:47,360 --> 00:54:53,840
AI and explainability in the sense of right now the regulatory framework in healthcare
900
00:54:53,840 --> 00:55:00,600
requires us to an extent to understand what the AI is doing, to understand the networks
901
00:55:00,600 --> 00:55:04,320
or the processes behind the outcomes.
902
00:55:04,320 --> 00:55:07,440
When do we let go of that need for explainability?
903
00:55:07,440 --> 00:55:13,840
If the AI is providing amazing outcomes, maybe outcomes better than humans, when do we say,
904
00:55:13,840 --> 00:55:20,360
okay, let us let this algorithm do its job, provide us with care, with decisions on when
905
00:55:20,360 --> 00:55:25,240
to operate, when not to operate, what drugs to use even, what diagnoses, and maybe we
906
00:55:25,240 --> 00:55:27,640
don't even answer the diagnoses.
907
00:55:27,640 --> 00:55:30,760
At what point do we let go of that need for explainability?
908
00:55:30,760 --> 00:55:34,840
Because by not doing so, we're limiting the scope of AI, I feel.
909
00:55:34,840 --> 00:55:35,840
Yeah.
910
00:55:35,840 --> 00:55:40,320
So interestingly, like radiology has been on the forefront of this, right?
911
00:55:40,320 --> 00:55:44,480
And so through our clinical trial company, we did the approvals for a lot of these AI
912
00:55:44,480 --> 00:55:45,480
products.
913
00:55:45,480 --> 00:55:51,160
The FDA as a regulatory body has already given blessing on not knowing how the AI works.
914
00:55:51,160 --> 00:55:55,520
So in a compositional neural network, in a pure CNN, it truly is a black box, right?
915
00:55:55,520 --> 00:55:57,640
So it's input in, input out, back test.
916
00:55:57,640 --> 00:56:00,960
So no one understands how, I mean, there is no understanding of how the black box works
917
00:56:00,960 --> 00:56:03,880
per se, but those algorithms are approved.
918
00:56:03,880 --> 00:56:09,720
So we have FDA approval for several algorithms that nobody knows how they work, quote unquote,
919
00:56:09,720 --> 00:56:10,720
right?
920
00:56:10,720 --> 00:56:11,720
Oh, perfect.
921
00:56:11,720 --> 00:56:17,400
So AI exists, and the FDA is moving through this in terms of defining, there's a whole
922
00:56:17,400 --> 00:56:18,600
host of secondary.
923
00:56:18,600 --> 00:56:24,720
So AI is going through this evolution of sort of what I call AI 1.0, which has been traditionally
924
00:56:24,720 --> 00:56:28,280
sort of detection technology, and it's not controversial, right?
925
00:56:28,280 --> 00:56:30,660
Is there a mass on this picture?
926
00:56:30,660 --> 00:56:33,200
Is there an abnormality in the CBC?
927
00:56:33,200 --> 00:56:35,160
Is there whatever it may be?
928
00:56:35,160 --> 00:56:36,480
It's not controversial in understanding.
929
00:56:36,480 --> 00:56:40,100
It's a detection technology, and there's been detection technology for a long time.
930
00:56:40,100 --> 00:56:41,560
No one has an issue with that.
931
00:56:41,560 --> 00:56:45,880
The detection is getting better, and the detection is getting to a level where we're asymptotic
932
00:56:45,880 --> 00:56:50,480
and where you cannot, as computing power goes to, the cost of computing goes to zero, this
933
00:56:50,480 --> 00:56:54,160
gets better and you can detect better and be more holistic about it.
934
00:56:54,160 --> 00:56:58,840
This next generation of AI is, which I don't think we're at, which, and I'm going to get
935
00:56:58,840 --> 00:57:02,920
to your point, is sort of where there's an interpretation of what is detected.
936
00:57:02,920 --> 00:57:04,920
So you're making an evaluation.
937
00:57:04,920 --> 00:57:08,120
And so for example, you find a mass on a mammogram.
938
00:57:08,120 --> 00:57:14,440
There's a company that has a heat map that it takes and ingests your BRCA, it ingests
939
00:57:14,440 --> 00:57:18,320
your family history, it ingests your diet, a whole bunch of other risk factors to give
940
00:57:18,320 --> 00:57:22,480
an assessment of whether or not that mass is going to turn into a cancer.
941
00:57:22,480 --> 00:57:25,280
1.0 tells you, is it a cancer or not?
942
00:57:25,280 --> 00:57:30,240
And if it's not, 2.0 tells you, based on all these other risk factors, it's going to become
943
00:57:30,240 --> 00:57:31,380
a cancer.
944
00:57:31,380 --> 00:57:35,600
So that's sort of 2.0, and I think 3.0 is what you're talking about, where it's a true
945
00:57:35,600 --> 00:57:36,600
decision maker.
946
00:57:36,600 --> 00:57:42,160
I think as a society, we probably don't want computers to make that decision, open AI or
947
00:57:42,160 --> 00:57:43,720
all the money, fear and all that.
948
00:57:43,720 --> 00:57:51,360
But I think it's inevitable that a component of what we do will become, and AI will adjunct
949
00:57:51,360 --> 00:57:52,360
what we do.
950
00:57:52,360 --> 00:57:54,880
And imaging is a great example, right?
951
00:57:54,880 --> 00:58:01,120
I think in 2022, as long as I am a licensed physician who is trained, who's willing to
952
00:58:01,120 --> 00:58:07,240
sign off on something, I can use the AI to adjunct and augment what I do.
953
00:58:07,240 --> 00:58:10,800
There's an algorithm that can find a rib fracture on a CT scan.
954
00:58:10,800 --> 00:58:13,880
Does anyone in the world have a problem with me using that algorithm?
955
00:58:13,880 --> 00:58:18,600
Absolutely not, as long as the algorithm detects and I say, I agree, and that's a rib fracture.
956
00:58:18,600 --> 00:58:23,080
So that, I think we're there, and that's where we are today.
957
00:58:23,080 --> 00:58:28,680
So the question becomes is, as we evolve, are we okay with AI making the ultimate decision?
958
00:58:28,680 --> 00:58:33,120
And then the constituents there are going to be, again, the provider, the payer, and
959
00:58:33,120 --> 00:58:34,720
the patient.
960
00:58:34,720 --> 00:58:42,680
I think the patient reflects on society, FDA, everybody else to make sure, just like the
961
00:58:42,680 --> 00:58:48,560
Consumer Protection Bureau protects consumers from ovens going on fire, right?
962
00:58:48,560 --> 00:58:52,200
We as a society expect these regulatory bodies to protect us.
963
00:58:52,200 --> 00:58:53,800
So I don't think the patients make a decision.
964
00:58:53,800 --> 00:58:58,240
The patients say, if the FDA says it's okay, it's okay, as we've done with almost everything
965
00:58:58,240 --> 00:58:59,680
else.
966
00:58:59,680 --> 00:59:04,280
The providers, I think as long as they're getting an economic benefit or do not lose
967
00:59:04,280 --> 00:59:07,400
an economic benefit, are absolutely fine using it.
968
00:59:07,400 --> 00:59:12,440
So in my rib fracture example, if insurance is willing to pay for me to use the rib fracture
969
00:59:12,440 --> 00:59:14,800
algorithm, I have no problem using it.
970
00:59:14,800 --> 00:59:16,920
Makes me a better doctor, better diagnostician.
971
00:59:16,920 --> 00:59:20,040
I miss less fractures all day long.
972
00:59:20,040 --> 00:59:23,640
So it comes down to the payer, right?
973
00:59:23,640 --> 00:59:26,360
And it comes down to money, which is what all of this comes down to.
974
00:59:26,360 --> 00:59:28,920
So the payer says, why am I willing to pay for this?
975
00:59:28,920 --> 00:59:32,760
The only reason I'm willing to pay for this, honestly, right, if we're true to ourselves,
976
00:59:32,760 --> 00:59:35,600
is that it reduces my cost of providing care.
977
00:59:35,600 --> 00:59:39,160
So if we go back to my rib fracture example, and I use this specifically, if you have a
978
00:59:39,160 --> 00:59:43,720
rib fracture on a CT scan that's not significantly displaced, you know what we tell you to do?
979
00:59:43,720 --> 00:59:45,960
Take two Advil and we'll call you in the morning, right?
980
00:59:45,960 --> 00:59:47,680
There's no treatment for that per se.
981
00:59:47,680 --> 00:59:49,880
I'm not talking about a flail chest or a pneumothorax.
982
00:59:49,880 --> 00:59:52,500
I'm just talking about a non-displaced rib fracture.
983
00:59:52,500 --> 00:59:56,200
So at the end of the day for the payer, did it really matter if I found that rib fracture
984
00:59:56,200 --> 00:59:58,280
probably not, right?
985
00:59:58,280 --> 01:00:02,160
Academically, for us, it matters that we don't miss a finding.
986
01:00:02,160 --> 01:00:03,160
For the patient, it matters.
987
01:00:03,160 --> 01:00:06,440
Now they have an explanation for their right side of chest pain.
988
01:00:06,440 --> 01:00:11,320
But the payer, and this at some point was supposition, now it's playing out because
989
01:00:11,320 --> 01:00:16,720
I've seen many, many, many AI companies that have closed shop because they went to the
990
01:00:16,720 --> 01:00:18,640
payer and the payer said no.
991
01:00:18,640 --> 01:00:20,820
They went to the patient and the patient said no.
992
01:00:20,820 --> 01:00:24,500
They went to the hospital, the hospital said no, we're not paying for this.
993
01:00:24,500 --> 01:00:26,800
And they have to close shop because they couldn't find a payer.
994
01:00:26,800 --> 01:00:30,920
So I think that's what ends up driving some of this stuff at the end of the day is, is
995
01:00:30,920 --> 01:00:37,480
there a economic benefit to that algorithm independent of, lots of time there's a clinical
996
01:00:37,480 --> 01:00:41,020
benefit and there's no question there's a clinical benefit.
997
01:00:41,020 --> 01:00:43,520
But that's not what the driver of the technology is.
998
01:00:43,520 --> 01:00:45,740
The driver is who's going to pay for it.
999
01:00:45,740 --> 01:00:51,120
So that's experientially what I've learned as an investor is like when we have these
1000
01:00:51,120 --> 01:00:53,760
companies that come, we say, who's going to pay for this?
1001
01:00:53,760 --> 01:00:56,120
Oh, well, we'll figure that out later.
1002
01:00:56,120 --> 01:00:57,120
Not investing in your company.
1003
01:00:57,120 --> 01:01:02,640
Or I'm going to get a CPT code and I'm going to get reimbursement for this.
1004
01:01:02,640 --> 01:01:03,640
Not investing in that.
1005
01:01:03,640 --> 01:01:07,880
You have not been through the system because the payer is not going to pay for that unless
1006
01:01:07,880 --> 01:01:09,760
you can prove benefit.
1007
01:01:09,760 --> 01:01:16,440
How far are we from the AI being the provider, at least for certain verticals like, you know,
1008
01:01:16,440 --> 01:01:18,960
UTI and birth control refills?
1009
01:01:18,960 --> 01:01:19,960
Yeah.
1010
01:01:19,960 --> 01:01:23,680
I mean, I don't know if you've used chat GPT yet, but I haven't.
1011
01:01:23,680 --> 01:01:25,200
Yeah, I mean, just type in.
1012
01:01:25,200 --> 01:01:26,200
I got a cold one.
1013
01:01:26,200 --> 01:01:27,560
I mean, chat GPT is amazing.
1014
01:01:27,560 --> 01:01:33,120
So AI inner sort of generational AI, I think, is at that level now.
1015
01:01:33,120 --> 01:01:34,120
So I think we're there.
1016
01:01:34,120 --> 01:01:40,960
I mean, if it's algorithmic algorithmic treatment, which is in essence what you know, there's
1017
01:01:40,960 --> 01:01:44,600
a whole host of companies doing asynchronous care, right?
1018
01:01:44,600 --> 01:01:50,240
You have an app, you log on, you say, I've got a cough, I've got a fever, I've got green
1019
01:01:50,240 --> 01:01:52,840
sputum, I've got shortness of breath.
1020
01:01:52,840 --> 01:01:55,120
Pretty high chance you got a pneumonia.
1021
01:01:55,120 --> 01:01:58,360
And if it's hurting on the right side, it's in the right lower lobe, right?
1022
01:01:58,360 --> 01:02:03,260
So that asynchronous data capture, they then send you for a chest x-ray and some labs,
1023
01:02:03,260 --> 01:02:05,120
and then they get that result.
1024
01:02:05,120 --> 01:02:07,400
And then they, you know, you get antibiotics.
1025
01:02:07,400 --> 01:02:10,800
There isn't a need for a level five or an ND visit.
1026
01:02:10,800 --> 01:02:13,640
I mean, you can go see a PA or maybe an NP if you need to.
1027
01:02:13,640 --> 01:02:19,360
But a lot, you know, for the most part, that visit doesn't add AI and even chat GPT, which
1028
01:02:19,360 --> 01:02:24,520
sounds crazy, but conversational AI on asynchronous data capture and treatment, I think is there
1029
01:02:24,520 --> 01:02:25,520
today.
1030
01:02:25,520 --> 01:02:29,160
Now it goes back to the same problem of, you know, again, in the money, talking about the
1031
01:02:29,160 --> 01:02:33,480
money again, there's obviously a, you know, the litiginous part of it.
1032
01:02:33,480 --> 01:02:35,480
There's, you know, we worry about all that.
1033
01:02:35,480 --> 01:02:37,000
What happens when the AI makes a mistake?
1034
01:02:37,000 --> 01:02:38,000
Who do you sue?
1035
01:02:38,000 --> 01:02:39,000
All that kind of stuff.
1036
01:02:39,000 --> 01:02:45,480
But I think as it augments to the position in 2022, it's worth, I mean, there is capability
1037
01:02:45,480 --> 01:02:48,280
there and radiology has been one of those places where it's been first.
1038
01:02:48,280 --> 01:02:53,400
I mean, we augment what we do in mammography with cat with AI, right?
1039
01:02:53,400 --> 01:02:57,560
We bring up the mammogram, we look at it, we hit a button, the algorithm will highlight
1040
01:02:57,560 --> 01:02:59,240
a mass recalcitration.
1041
01:02:59,240 --> 01:03:02,960
We use that and use that to make a better interpretation.
1042
01:03:02,960 --> 01:03:07,280
So I think for the foreseeable future, it's AI augmenting the physician.
1043
01:03:07,280 --> 01:03:10,920
There is a day where I think it crosses over, but it has to get to a level of sensitivity
1044
01:03:10,920 --> 01:03:18,280
and specificity where it ensures providers feel comfortable that the system isn't going
1045
01:03:18,280 --> 01:03:19,280
to screw you.
1046
01:03:19,280 --> 01:03:20,280
Okay, perfect.
1047
01:03:20,280 --> 01:03:23,080
Amit, thanks so much for taking the time to be here.
1048
01:03:23,080 --> 01:03:24,080
Yeah, absolutely.
1049
01:03:24,080 --> 01:03:26,960
I had an amazing time and we'll have to do it again.
1050
01:03:26,960 --> 01:03:30,920
Yeah, I appreciate the time and I'm excited about what you guys are doing and love to help
1051
01:03:30,920 --> 01:03:35,760
out with the forum and as people sort of make their way through investments, you know, feel
1052
01:03:35,760 --> 01:03:36,760
free to reach out.
1053
01:03:36,760 --> 01:03:37,760
I'm happy to help in any way.
1054
01:03:37,760 --> 01:03:38,760
Thanks.
1055
01:03:38,760 --> 01:03:41,760
Amit.